GeneSight employs a proprietary algorithm to analyze 12 genes and assess how they impact patients’ ability to process dozens of psychotropic medications. The test report buckets depression treatments as red (significant gene-drug interaction), yellow (moderate gene-drug interaction), or green (use as directed.) When the test report shows that patients are on red or yellow medications, their doctors should consider changing the drug or dose, while patients on green medications don’t require a medication change.
Researchers further evaluated patients who entered the study on red medications and either remained on red medications or were switched to yellow or green drugs. Remission rates were 153 percent higher, response rates were 71 percent higher, and symptom improvement rates were 59 percent higher when patients were switched from red to yellow or green meds — all statistically significant changes.
This analysis “establishes a new standard of care” for physicians by demonstrating that patients on red medications must be identified and have their medications modified, said Dechairo. “This switching analysis has also been an important point in our payor discussions, as utilization management programs can focus on switching patients from red medications, which would deliver results even better than those in the GUIDED study,” he said.
One prior cost-effectiveness study using drug claims data showed that using GeneSight can increase treatment adherence and save an average of $1,036 per year per patient, while another study using commercial claims data showed GeneSight’s potential to save $1,556 per patient by reducing disability claims, medical utilization, workplace absence.
Currently, the more than 300,000 GeneSight tests Myriad sells per year are largely ordered by psychiatrists. Once there is greater reimbursement traction, Myriad is planning a significant marketing push into the primary care market, including direct-to-patient advertising for the test, according to Capone.
GeneSight, which is a lab-developed test (LDT) performed in a CLIA-certified lab, must be ordered by physicians.
Capone noted that the FDA has publicly stated that it will continue to practice enforcement discretion for LDTs, and leave it up to legislators to reform diagnostic regulations that may or may not bring LDTs under the agency’s oversight. In December, legislators in the House of Representatives and the Senate incorporated the FDA’s ideas for diagnostics regulatory reform into a draft bill that features a pre-certification program that labs could use to bring the majority of new diagnostics to market, while having to submit around 10 percent of tests for premarket review. READ MORE…
Did your doctor or friendly pharmacist tell you that the flu vaccine could put your mental health at risk?
The connection between inflammation and depression is so well known to researchers that scientists inject animals with pro-inflammatory substances to induce depression.
New Study: Vaccines Linked to Decline in Mental Health and Social Interaction – A Cause of Increase in Mass School Shootings?
CCHR NEWSLETTER: CAN VACCINES CAUSE PSYCHIATRIC DISORDERS?
The authors statistically analyzed insurance claims data between 2002 and 2007 for thousands of children ages 6 to 15 for any relationships between various vaccinations (influenza, tetanus & diphtheria, hepatitis A, hepatitis B, meningitis, varicella) and various subsequent psychiatric diagnoses (obsessive-compulsive disorder, anorexia nervosa, tic disorders, attention deficit hyperactivity disorder, major depressive disorder, bipolar disorder).
The overall conclusion of this analysis implies that the onset of some psychiatric disorders may be related to some children having recently received a vaccination.
Temporal Association of Certain Neuropsychiatric Disorders Following Vaccination of Children and Adolescents: A Pilot Case–Control Study
Description: A psilocybin mushroom is one of a polyphyletic group of fungi that contain any of various psychedelic compounds, including psilocybin, psilocin, and baeocystin. Common, colloquial terms for psilocybin mushrooms include psychedelic mushrooms, magic mushrooms, shrooms, and mush.
Johns Hopkins University studied psilocybin in particular and found that one-third of all participants reported that the experience was the single most spiritually significant moment of their lives and more than two-thirds reported it was among the top five most spiritually significant experiences. Two months after the study, 79% of the participants reported increased well-being or satisfaction; friends, relatives, and associates confirmed this. Read more…
VLA Comment and Warning:
10% of Caucasians and percentages of Asians and Blacks do not have the Liver enzyme, Cytochrome P450 2D6 necessary to metabolize psilocybin. They become “psychotic”. 79% of the participants according to Hopkins Univ. experience increased well being. What about the 21%? Did they experience psychosis? Every patient and every person in psychiatric drug testing should have their genetics tested prior to implementation. A simple gene test is covered by medicare and medicaid. See:
Depression is on the rise around the world and, according to one author, the World Health Organization (WHO) has stated that approximately 300 million people worldwide suffer from this debilitating disorder
Author, Amy Morin, LCSW, wrote in her article, Depression Statistics Everyone Should Know, that in the United States alone, 16.2 million adults have experienced a major depressive episode in the past year.
Dr.Kelly Brogan’s paper outlined the strong possibility that the aluminum adjuvant that is currently being used in at least 18 childhood vaccinations may be responsible for the increase in long-term brain inflammation, neurological complications and autoimmunity. She stated that:
“One of the most relevant aluminum-containing vaccines is Gardasil, responsible for more than 34000 reported adverse events,and now Gardasil 9, which contains twice the aluminum dose (ie, now with 500 μg per 3 recommended doses).”
The Pandemic of Iatrogenocide, Associated with Drug and Vaccine Poisoning Causing Mitochondrial and DNA Disruption.
DR. GARY KOHL…READ ARTICLE
“Mitochondrial damage is now understood to play a role in a wide range of seemingly unrelated disorders such as schizophrenia, diabetes, Parkinson’s disease, chronic fatigue syndrome, and nonalcoholic steatohepatitis. Recently it has become known that iatrogenic (physician or treatment-caused) mitochondrial damage explains many adverse reactions from medications.” — John Neustadt, MD and Steven Pieczenik, MD
VLA COMMENT: And Autism, vaccine induced mitochondria damage underlying Autism
“All classes of psychotropic drugs have been documented to damage mitochondria, as have statin medications, analgesics such as acetaminophen, and many others.” – John Neustadt, MD and Steven Pieczenik, MD
Near infrared radiation rescues mitochondrial dysfunction in cortical neurons after oxygen-glucose deprivation
More About Serotonin.
The word comes from the combination of sero- (serum) + tonic (from Greek tonos string or stretching) + -in (from Latin -ina a term used to form words). It was first named in 1948, although its effects had likely been observed since 1868.
Serotonin is a neurotransmitter hormone synthesized in the adrenal glands and elsewhere in the body from the essential amino acid tryptophan (chemical formula C10H12N2O, also called 5-hydroxytryptamine), found in the brain, blood, and mostly the digestive tract, which allows nerve cells throughout the body to communicate and interact with each other.
Today, with militaries of the world awash in psychiatry and psychiatric drugs, 23 soldiers and veterans are committing suicide every day.
Psychiatrists say we need more psychiatry. But should we trust them? Or is psychiatry the hidden enemy?
Featuring interviews with over 80 soldiers and experts, this penetrating documentary shatters the facade to reveal the real culprits who are destroying our world’s militaries from within.
Psychiatry Creates Disorder
The real reason we discuss this at all is because the psychiatric mental health care industry is a disorder machine. This is something you need to know. Consider the litany of psychiatric treatments —
1. Psychiatric drugs interrupt the normal functioning of the body and mind. Drugs break into, in most cases, the routine rhythmic flows and activities of the nervous system. Sure, the suppression of unwanted pains or emotions may seem to be an improvement, but the body can only take so much. Quickly or slowly, the systems break down. Human physiology was not designed for the continuous manufacture of euphoric, tranquilizing, or antidepressant sensations. Yet it is forced into this enterprise by psychiatric drugs.
Like a car run on rocket fuel, you may be able to get it to run a thousand miles an hour, but the tires, the engine, the internal parts, were never meant for this. The machine flies apart. Bizarre things happen: addiction, exhaustion, diminished sexual desire, trembling, nightmares, hallucinations, and psychosis. Side effects are, in fact, the body’s natural response to having a chemical disrupt its normal functioning. Once the drug has worn off, the original problem remains. As a solution or cure to life’s problems, psychotropic drugs do not work. They cause disorder.
2. Electro-Convulsive Therapy (ECT), or shock therapy, interrupts the normal functioning of the brain. ECT creates a nerve–wracking convulsion of long duration. And it leaves irreversible brain damage and disorder. Why, then, is it used so frequently? There are two reasons. 1) It is lucrative, and 2) The actual purpose of shock treatment is to create brain damage. In 1942, the psychiatrist Abraham Myerson said: “The reduction of intelligence is an important factor in the curative process.” Creating disorder, ECT makes a patient for life, ensuring continued income for psychiatry.
3. Other direct assaults on the brain — psycho-surgery (cutting out part of the brain); transcranial magnetic stimulation; vagus nerve stimulation — all involve physical damage and disorder to the brain.
4. Physical restraints qualify as “assault and battery” in every respect except one; they are lawful. Psychiatry has placed itself above the law, from where it can assault and batter its unfortunate victims with a complete lack of accountability, all in the name of “treatment.” You might suppose that restraints impose order, since they limit movement, until you consider that they are enforced against one’s will. When you coerce order you get punishment, which is really order gone bad. You might call it “negative order”, because the emotional component is so unpleasant. READ MORE…
Some specific pharmaceutical drugs that should not be combined with MAOIs (some are mild risks, others serious):
– Albuterol (Proventil, Ventolin)
– Amantadine hydrochloride (Symmetrel)
– Amoxapine (Asendin)
– Benmoxinb (Nerusil, Neuralex)
– Benzphetamine (Didrex)
– Brofaromine (Consonar)
– Bupropion (Wellbutrin)
– Buspirone (BuSpar)
– Carbamazepine (Tegretol, Epitol)
– Citalopram (Celexa)
– Clomipramine (Anafranil)
– Cyclobenzaprine (Flexeril)
– Cyclizine (Marezine)
– Desipramine (Pertofrane, Norpramin)
– Dextroamphetamine (Dexedrine)
– Dextromethorphan (DXM)
– Dienolide kavapyrone desmethoxyyangonin
– Disopyramide (Norpace)
– Disulfiram (Antabuse)
– Dopamine (Intropin)
– Doxepin (Sinequan)
– Duloxetine (Cymbalta)
– Epinephrine (Adrenalin)
– Escitalopram (Lexapro)
– Fenfluramine (Pondimin)
– Flavoxate Hydrochloride (Urispas)
– Fluoxetine (Prozac)
– Furazolidone (Furoxone)
– Guanadrel (Hylorel)
– Guanethidine (Ismelin)
– Hydralazine (Apresoline)
– Imipramine (Tofranil)
– Iproniazid (Marsilid, Iprozid, Ipronid, Rivivol, Propilniazida)
– Iproclozide (Sursum)
– Isocarboxazid (Marplan)
– Isoniazid (Laniazid, Nydrazid)
– Isoniazid rifampin (Rifamate, Rimactane)
– Isoproterenol (Isuprel)
– L-dopa (Sinemet)
– Lazabemide (Pakio, Tempium)
– Levodopa (Dopar, Larodopa)
– Linezolid (Zyvox, Zyvoxid)
– Lithium (Eskalith)
– Loratadine (Claritin)
– Maprotiline (Ludiomil)
– Mebanazine (Actomol)
– Meperidine (Demerol)
– Metaproterenol (Alupent, Metaprel)
– Metaraminol (Aramine)
– Metfendrazine (Inkazan)
– Methamphetamine (Desoxyn)
– Methyldopa (Aidomet)
– Methylphenidate (Ritalin)
– Minaprine (Cantor)
– Mirtazapine (Remeron)
– Moclobemide (Aurorix, Manerix)
– Montelukast (Singulair)
– Nialamide (Niamid)
– Norepinephrine (Levophed)
– Nortriptyline (Aventyl)
– Octamoxin (Ximaol, Nimaol)
– Oxybutynin chloride (Ditropan)
– Oxymetazoline (Afrin, Dimetapp)
– Orphenadrine (Norflex)
– Pargyline (Eutonyl)
– Paroxetine (Paxil)
– Pemoline (Cylert)
– Pethedine (Demerol)
– Phendimetrazine (Plegiline)
– Phenelzine (Nardil)
– Phenelzine (Nardil, Nardelzine)
– Pheniprazine (Catron)
– Phenoxypropazine (Drazine)
– Phenylephrine (Dimetane, Dristan decongestant, Neo-Synephrine)
– Phenylpropanolamine (found in many cold medicines)
– Phenelzine (Nardil)
– Pirlindole (Pirazidol)
– Procarbazine (Matulane)
– Procainamide (Pronestyl)
– Protriptyline (Vivactil)
– Oxymetazoline (Afrin)
– Quinidine (Quinidex)
– Rasagiline (Azilect)
– Reserpine (Serpasil)
– Selegiline (Eldepryl, Emsam, Zelapar)
– Sertraline (Zoloft)
– Sumatriptan (Imitrex)
– Terfenadine (Seldane-D)
– Theophylline (Theo-Dur)
– Thioridazine (Mellaril)
– Toloxatone (Humoryl)
– Tranylcypromine (Parnate)
– Tricyclic antidepressants (Amitriptyline, Elavil)
– Trimipramine (Surmontil)
– Venlafaxine (Effexor)
– Ziprasidone (Geodon)