Category Archives: Psyche Ward

PHARMACOGENETIC TEST SIGNIFICANTLY INCREASE REMISSION OF MENTAL ILLNESS (DEPRESSION)

GeneSight employs a proprietary algorithm to analyze 12 genes and assess how they impact patients’ ability to process dozens of psychotropic medications. The test report buckets depression treatments as red (significant gene-drug interaction), yellow (moderate gene-drug interaction), or green (use as directed.) When the test report shows that patients are on red or yellow medications, their doctors should consider changing the drug or dose, while patients on green medications don’t require a medication change.

Researchers further evaluated patients who entered the study on red medications and either remained on red medications or were switched to yellow or green drugs. Remission rates were 153 percent higher, response rates were 71 percent higher, and symptom improvement rates were 59 percent higher when patients were switched from red to yellow or green meds — all statistically significant changes.

This analysis “establishes a new standard of care” for physicians by demonstrating that patients on red medications must be identified and have their medications modified, said Dechairo. “This switching analysis has also been an important point in our payor discussions, as utilization management programs can focus on switching patients from red medications, which would deliver results even better than those in the GUIDED study,” he said.

One prior cost-effectiveness study using drug claims data showed that using GeneSight can increase treatment adherence and save an average of $1,036 per year per patient, while another study using commercial claims data showed GeneSight’s potential to save $1,556 per patient by reducing disability claims, medical utilization, workplace absence.

Currently, the more than 300,000 GeneSight tests Myriad sells per year are largely ordered by psychiatrists. Once there is greater reimbursement traction, Myriad is planning a significant marketing push into the primary care market, including direct-to-patient advertising for the test, according to Capone.

GeneSight, which is a lab-developed test (LDT) performed in a CLIA-certified lab, must be ordered by physicians.

Capone noted that the FDA has publicly stated that it will continue to practice enforcement discretion for LDTs, and leave it up to legislators to reform diagnostic regulations that may or may not bring LDTs under the agency’s oversight. In December, legislators in the House of Representatives and the Senate incorporated the FDA’s ideas for diagnostics regulatory reform into a draft bill that features a pre-certification program that labs could use to bring the majority of new diagnostics to market, while having to submit around 10 percent of tests for premarket review.  READ MORE…

ABSTRACT OF STUDY

 

New Study: Vaccines linked to Increase in mass school shootings and suicides

New Study: Vaccines Linked to Decline in Mental Health and Social Interaction – A Cause of Increase in Mass School Shootings?

CCHR NEWSLETTER:  CAN VACCINES CAUSE PSYCHIATRIC DISORDERS?

The authors statistically analyzed insurance claims data between 2002 and 2007 for thousands of children ages 6 to 15 for any relationships between various vaccinations (influenza, tetanus & diphtheria, hepatitis A, hepatitis B, meningitis, varicella) and various subsequent psychiatric diagnoses (obsessive-compulsive disorder, anorexia nervosa, tic disorders, attention deficit hyperactivity disorder, major depressive disorder, bipolar disorder).

The overall conclusion of this analysis implies that the onset of some psychiatric disorders may be related to some children having recently received a vaccination.

READ NEWSLETTER…

Temporal Association of Certain Neuropsychiatric Disorders Following Vaccination of Children and Adolescents: A Pilot Case–Control Study

CCHR finds Study: Association of vaccines and psychiatric disorders in children and adolescents

Magic Mushrooms (Psilocybin) for Seniors

Psilocybin mushroom

Fungus

Description: A psilocybin mushroom is one of a polyphyletic group of fungi that contain any of various psychedelic compounds, including psilocybin, psilocin, and baeocystin. Common, colloquial terms for psilocybin mushrooms include psychedelic mushrooms, magic mushrooms, shrooms, and mush.

Johns Hopkins University studied psilocybin in particular and found that one-third of all participants reported that the experience was the single most spiritually significant moment of their lives and more than two-thirds reported it was among the top five most spiritually significant experiences. Two months after the study, 79% of the participants reported increased well-being or satisfaction; friends, relatives, and associates confirmed this. Read more…

VLA Comment and Warning:

10% of Caucasians and percentages of Asians and Blacks do not have the Liver enzyme, Cytochrome P450 2D6 necessary to metabolize psilocybin.  They become “psychotic”. 79% of the participants according to Hopkins Univ. experience increased well being.  What about the 21%?  Did they experience psychosis?  Every patient and every person in psychiatric drug testing should have their genetics tested prior to implementation.  A simple gene test is covered by medicare and medicaid.  See:

Depression/Anxiety: Professionals World Wide blame Aluminum in Vaccines!

 

Depression is on the rise around the world and, according to one author, the World Health Organization (WHO) has stated that approximately 300 million people worldwide suffer from this debilitating disorder

Author, Amy Morin, LCSW, wrote in her article, Depression Statistics Everyone Should Know, that in the United States alone, 16.2 million adults have experienced a major depressive episode in the past year.

Dr.Kelly Brogan’s  paper outlined the strong possibility that the aluminum adjuvant that is currently being used in at least 18 childhood vaccinations may be responsible for the increase in long-term brain inflammation, neurological complications and autoimmunity. She stated that:

“One of the most relevant aluminum-containing vaccines is Gardasil, responsible for more than 34000 reported adverse events,and now Gardasil 9, which contains twice the aluminum dose (ie, now with 500 μg per 3 recommended doses).”

READ MORE…

The Pandemic of Iatrogenocide: Emphasis on the MITCHONDRIA

The Pandemic of Iatrogenocide, Associated with Drug and Vaccine Poisoning Causing Mitochondrial and DNA Disruption.

DR. GARY KOHL…READ ARTICLE

“Mitochondrial damage is now understood to play a role in a wide range of seemingly unrelated disorders such as schizophrenia, diabetes, Parkinson’s disease, chronic fatigue syndrome, and nonalcoholic steatohepatitis. Recently it has become known that iatrogenic (physician or treatment-caused) mitochondrial damage explains many adverse reactions from medications.” John Neustadt, MD and Steven Pieczenik, MD

VLA COMMENT:  And Autism, vaccine induced mitochondria damage underlying Autism

 “All classes of psychotropic drugs have been documented to damage mitochondria, as have statin medications, analgesics such as acetaminophen, and many others.” – John Neustadt, MD and Steven Pieczenik, MD

 

Near infrared radiation rescues mitochondrial dysfunction in cortical neurons after oxygen-glucose deprivation

Read study

 

 

CCHR: Serotonin and Psychiatric Drugs

More About Serotonin.

The word comes from the combination of sero- (serum) + tonic (from Greek tonos string or stretching) + -in (from Latin -ina a term used to form words). It was first named in 1948, although its effects had likely been observed since 1868.

Serotonin is a neurotransmitter hormone synthesized in the adrenal glands and elsewhere in the body from the essential amino acid tryptophan (chemical formula C10H12N2O, also called 5-hydroxytryptamine), found in the brain, blood, and mostly the digestive tract, which allows nerve cells throughout the body to communicate and interact with each other.

READ CCHR Newsletter
Today, with militaries of the world awash in psychiatry and psychiatric drugs, 23 soldiers and veterans are committing suicide every day.
Psychiatrists say we need more psychiatry. But should we trust them? Or is psychiatry the hidden enemy?
Featuring interviews with over 80 soldiers and experts, this penetrating documentary shatters the facade to reveal the real culprits who are destroying our world’s militaries from within.

Watch The Hidden Enemy — Inside Psychiatry’s Hidden Agenda

PSYCHIATRY DANGER (CCHR)

Psychiatry Creates Disorder

The real reason we discuss this at all is because the psychiatric mental health care industry is a disorder machine. This is something you need to know.  Consider the litany of psychiatric treatments —

1. Psychiatric drugs interrupt the normal functioning of the body and mind. Drugs break into, in most cases, the routine rhythmic flows and activities of the nervous system. Sure, the suppression of unwanted pains or emotions may seem to be an improvement, but the body can only take so much. Quickly or slowly, the systems break down. Human physiology was not designed for the continuous manufacture of euphoric, tranquilizing, or antidepressant sensations. Yet it is forced into this enterprise by psychiatric drugs.

Like a car run on rocket fuel, you may be able to get it to run a thousand miles an hour, but the tires, the engine, the internal parts, were never meant for this. The machine flies apart. Bizarre things happen: addiction, exhaustion, diminished sexual desire, trembling, nightmares, hallucinations, and psychosis. Side effects are, in fact, the body’s natural response to having a chemical disrupt its normal functioning. Once the drug has worn off, the original problem remains. As a solution or cure to life’s problems, psychotropic drugs do not work. They cause disorder.

2. Electro-Convulsive Therapy (ECT), or shock therapy, interrupts the normal functioning of the brain. ECT creates a nerve–wracking convulsion of long duration. And it leaves irreversible brain damage and disorder. Why, then, is it used so frequently? There are two reasons. 1) It is lucrative, and 2) The actual purpose of shock treatment is to create brain damage. In 1942, the psychiatrist Abraham Myerson said: “The reduction of intelligence is an important factor in the curative process.” Creating disorder, ECT makes a patient for life, ensuring continued income for psychiatry.

3. Other direct assaults on the brain — psycho-surgery (cutting out part of the brain); transcranial magnetic stimulation; vagus nerve stimulation — all involve physical damage and disorder to the brain.

4. Physical restraints qualify as “assault and battery” in every respect except one; they are lawful. Psychiatry has placed itself above the law, from where it can assault and batter its unfortunate victims with a complete lack of accountability, all in the name of “treatment.” You might suppose that restraints impose order, since they limit movement, until you consider that they are enforced against one’s will. When you coerce order you get punishment, which is really order gone bad. You might call it “negative order”, because the emotional component is so unpleasant. READ MORE…

Foods and Medications to Avoid with MAOIs

Some specific pharmaceutical drugs that should not be combined with MAOIs (some are mild risks, others serious):

– Actifed
– Adderall
– Alaproclate
– Albuterol (Proventil, Ventolin)
– Amantadine hydrochloride (Symmetrel)
– Amiflamine
– Amineptine
– Amitriptaline
– Amoxapine (Asendin)
– Atomoxedine
– Bazinaprine
– Befloxetone’
– Befol
– Benadryl
– Benmoxinb (Nerusil, Neuralex)
– Benylin
– Benzedrine
– Benzphetamine (Didrex)
– Bicifadine
– Brasofensine
– Brofaromine (Consonar)
– Buprenorphine
– Bupropion (Wellbutrin)
– Buspirone (BuSpar)
– Butriptyline
– Carbamazepine (Tegretol, Epitol)
– Chlorpheniramine
– Chlor-Trimeton
– Cimoxetone
– Citalopram (Celexa)
– Clomipramine (Anafranil)
– Clorgyline
– Codeine
– Cyclobenzaprine (Flexeril)
– Cyclizine (Marezine)
– D-deprenyl
– Dapoxotine
– Desipramine (Pertofrane, Norpramin)
– Desvenlafaxine
– Dextroamphetamine (Dexedrine)
– Dextromethorphan (DXM)
– Dibenzepin
– Dienolide kavapyrone desmethoxyyangonin
– Diethylpropion
– Disopyramide (Norpace)
– Disulfiram (Antabuse)
– Dobutamine
– Dopamine (Intropin)
– Dosulepin
– Doxepin (Sinequan)
– Duloxetine (Cymbalta)
– Emsam
– Entacapone
– Ephedrine
– Epinephrine (Adrenalin)
– Escitalopram (Lexapro)
– Esuprone
– Etorphine
– Femoxitine
– Fenfluramine (Pondimin)
– Flavoxate Hydrochloride (Urispas)
– Fluoxetine (Prozac)
– Fluvoxamine
– Furazolidone (Furoxone)
– Gabapentin
– Guanethedine
– Guanadrel (Hylorel)
– Guanethidine (Ismelin)
– Hydralazine (Apresoline)
– Hydrazine
– 5-Hydroxytryptophan
– Imipramine (Tofranil)
– Iprindole
– Iproniazid (Marsilid, Iprozid, Ipronid, Rivivol, Propilniazida)
– Iproclozide (Sursum)
– Isocarboxazid (Marplan)
– Isoniazid (Laniazid, Nydrazid)
– Isoniazid rifampin (Rifamate, Rimactane)
– Isoproterenol (Isuprel)
– L-dopa (Sinemet)
– Ladostigil
– Lazabemide (Pakio, Tempium)
– Levodopa (Dopar, Larodopa)
– Linezolid (Zyvox, Zyvoxid)
– Lithium (Eskalith)
– Lofepramine
– Loratadine (Claritin)
– Maprotiline (Ludiomil)
– Mebanazine (Actomol)
– Medifoxamine
– Melitracen
– Meperidine (Demerol)
– Metaproterenol (Alupent, Metaprel)
– Metaraminol (Aramine)
– Metfendrazine (Inkazan)
– Methamphetamine (Desoxyn)
– Methyldopa (Aidomet)
– Methylphenidate (Ritalin)
– Metralindole
– Mianserin
– Milacimide
– Milnacipran
– Minaprine (Cantor)
– Mirtazapine (Remeron)
– Mofegeline
– Moclobemide (Aurorix, Manerix)
– Monomethylhydrazine
– Montelukast (Singulair)
– Nalbufrine
– Naloxone
– Naltrexone
– Nefazodone
– Nialamide (Niamid)
– Nisoxetine
– Nomifensine
– Norepinephrine (Levophed)
– Nortriptyline (Aventyl)
– Octamoxin (Ximaol, Nimaol)
– Oxybutynin chloride (Ditropan)
– Oxycodone
– Oxymetazoline (Afrin, Dimetapp)
– Oxymorphone
– Orphenadrine (Norflex)
– Pargyline (Eutonyl)
– Parnate
– Paroxetine (Paxil)
– Pemoline (Cylert)
– Percocet
– Pethedine (Demerol)
– Phendimetrazine (Plegiline)
– Phenelzine (Nardil)
– Phenergen
– Phenelzine (Nardil, Nardelzine)
– Pheniprazine (Catron)
– Phenmetrazine
– Phenoxypropazine (Drazine)
– Phentermine
– Phenylephrine (Dimetane, Dristan decongestant, Neo-Synephrine)
– Phenylhydrazine
– Phenylpropanolamine (found in many cold medicines)
– Phenelzine (Nardil)
– Pirlindole (Pirazidol)
– Procarbazine (Matulane)
– Procainamide (Pronestyl)
– Protriptyline (Vivactil)
– Pseudoephedrine
– Oxymetazoline (Afrin)
– Quinidine (Quinidex)
– Rasagiline (Azilect)
– Reboxetine
– Reserpine (Serpasil)
– Risperidone
– Salbutemol
– Salmeterol
– Selegiline (Eldepryl, Emsam, Zelapar)
– Sercloramine
– Sertraline (Zoloft)
– Sibutramine
– Sumatriptan (Imitrex)
– Terfenadine (Seldane-D)
– Tegretol
– Temaril
– Tesofensine
– Tetrindole
– Theophylline (Theo-Dur)
– Thesbutiaint
– Thioridazine (Mellaril)
– Tianeptine
– Tolcapone
– Toloxatone (Humoryl)
– Tramadol
– Tranylcypromine (Parnate)
– Trazodone
– Tricyclic antidepressants (Amitriptyline, Elavil)
– Trimipramine (Surmontil)
– Triptans
– Tyrima
– Vanoxerine
– Venlafaxine (Effexor)
– Viloxezine
– Yohimbine
– Zimelidine
– Ziprasidone (Geodon)

READ MORE…

The Causes Mental Illness: A 61 Year History of Pharmacogenetics suppressed by Pharma

Avram Goldstein: The Founder of Molecular Pharmacology
http://molpharm.aspetjournals.org/content/83/4/720

Summary:

As the Chair of the Department of Pharmacology with responsibility for training medical students in the use of drugs, he was fascinated by the kinetics of drug action. He and his wife Dody developed the plateau principle, which emerged from the recognition that the time to steady state for any drug administered continuously or repeatedly was dependent only on its rate of elimination. These developments drove his increasing desire to see the discipline of pharmacology, both in research and in medical and graduate education, as a science with a strong mechanistic and theoretical underpinning.

Avram was present in Moscow in 1961 when Marshall Nirenberg described his elucidation of the genetic code. With these seminal developments, Avram concluded that the time was ripe for the establishment of a journal devoted to mechanistic aspects of drug action at a molecular level.

Avram was able to persuade ASPET to publish the new journal, which would be called Molecular Pharmacology. “Suitable papers are those which describe applications of the methods of biochemistry, biophysics, genetics and molecular biology to pharmacologic or toxicologic problems…”

Avram, together with his Stanford faculty colleagues Lew Aronow and Sumner Kalman, were working on Principles of Drug Action (Goldstein et al., 1968), a pharmacology textbook that was new for its time in focusing only on basic principles underlying drug action and the longer-term responses of the body to the presence of drugs.

DRUG METABOLISM RESEARCH HAS A 61 YEAR HISTORY

VLA Comment: The field of Pharmacogenomics, Pharmacogenetics, Pharmacogenomics has a 61 YEAR HISTORY  well accepted research concerning drug metabolism.  Education in this field of research has been actively suppressed by Pharma. Anonymous sources in the field of education for medical students tells us that this information is actively suppressed as the pharmacuetical industry would loose billions and billions of dollars if the public knew.  Moreso  medical students and hospital psychiatrists and doctors in general from Pediatricians ot Oconologists  have virtually no knowledge or education of drug metabolism, yet they all provide prescriptions that are contraindicated, causing Medication (drug) induced psychosis.   90% of drugs need an active and mature liver system of Cytochrome P450 enzymes to metabolize and eliminate them from an individual’s body. A substantial percentage of Caucasians, Asians, Blacks have no activity to metabolize these modern drugs.  The results – increased (apparent) psychosis.

INCREASE IN PSYCHOSIS DIAGNOSES

The increase in psychosis diagnosis is actually the agressive poisoning of humanity by uneducated doctors from the cradle to the grave.  The increase in (apparent) mental illness and special needs is due to the inability of many individuals to eliminate, from the body, modern drugs (and streets drugs) such as SSRIs vaccine excipients.

VACCINES, THE BASIS OF MENTAL ILLNESS DIAGNOSES

Vaccines contain excipients that need a mature superfamily of Cytochrome P450 in order to be metabolize and successfully eliminated from the body of infants and children. The damage done to the physiology of a one hour old infant, injected with Aluminum (which interferes in Cyp 450 metabolism in the Hep B and Vitamin K shots),  and other vaccine excipients testifies to the basic underpinnings of the epidemic in Autism, ADHD, ADD, OCD, BiPolar,neurological, mitachondrial issues, depression, anxiety, panic attacks.   The misdiagnosis of mental illness by uneducated medical professionals who extensively prescribe psychiatric drugs and the push to vaccinate, to eliminate parental choice, to eliminate vaccine waivers appears to be an organized effort to debilite the entire emerging generations of humanity through the suppression of this Pharmacogenomic knowedge.  Note: There is no mandated continuing education in drug metabolism for practicing physicans; virtually no education for medical students; yet the prescrbing of medications and the push for vaccine compliance, school shootings, homicides and suicides, special needs education, is at an all time high.

CCHR Newsletter: Overview and layman understanding of Cyp 450, Pharmacogenetics, vaccines, psyche drugs,homicide, suicide.

Below, the American Society for Pharmacology and Experimental Therapeutics chronicled the discoveries and provided communications to advance the science of drug metabolism.

The Development of Drug Metabolism Research as Expressed in the Publications of ASPET: Part 2, 1959–1983
Patrick J. Murphy College of Pharmacy and Health Sciences, Butler University, Indianapolis, Indiana Received February 18, 2008; accepted February 27, 2008

ABSTRACT (2008):
In 25 years, (now 35 years) drug metabolism research went from using subcellular
particles of undefined content to an understanding of metabolism
at the molecular level. The discoveries of cytochrome P450, en-
zyme induction, reactive intermediates, and genetic polymor-
phisms were milestones in the field. New publications from the
American Society for Pharmacology and Experimental Therapeu-
tics chronicled the discoveries and provided communications to
advance the science of drug metabolism.

THE DISCOVERY OF CYTOCHROME P450 (1957)
The discovery of P450 and its function evolved from observations by Ryan and Engel that C-21 hydroxylations of progesterone and hydroxylated progesterones were catalyzed by a CO inhibitable en-zyme in the adrenal cortex (Ryan and Engel, 1957). They character-ized the reaction as belonging to the class of enzymes categorized by
Mason as “mixed-function oxidases” (Mason, 1957) and by Hayaishias “oxygenases” (Hayaishi, 1962).

THE ROLE OF GLUTATHIONE (depleted in AUTISM?)

The role of glutathione as a precursor of mercapturic acids was confirmed in 1959 (Bray et al., 1959a,b), 80 years after the discovery of these important elimination products by Baumann and Preuss (1879). In the following 25 years, there were over 150 papers in the ASPET journals referring to aspects of glutathione in metabolism. The role of glutathione as a scavenger of reactive intermediates was ofprimary interest, as exemplified by the finding of the glutathione conjugate of acetaminophen by Hinson et al. (1982) or the formation of mercapturic acids from cyclohexene epoxide in the rat (van Bla-deren et al., 1981).