Critical analysis of reference studies on the toxicokinetics of aluminum-based adjuvants
FDA regulations require safety testing of constituent ingredients in drugs (21 CFR 610.15). With the exception of extraneous proteins, no component safety testing is required for vaccines or vaccine schedules. The dosing of aluminum in vaccines is based on the production of antibody titers, not safety science. Here we estimate a Pediatric Dose Limit that considers body weight. We identify several serious historical missteps in past analyses of provisional safe levels of aluminum in vaccines, and provide updates relevant to infant aluminum exposure in the pediatric schedule considering pediatric body weight
VLA comment: Apparently it is okay with the CDC and Paul Offit at the Philadelphia Children’s Hospital that…and I quote and excerpt…the process which a small infant has to deal with excreting this poison or the consequences of retain the metal in the bones or the brains is inconsequental:
“We investigated hepatic P450 metabolism and drug pharmacokinetics in type 1 allergic mice induced by ovalbumin (OVA) emulsified with aluminum and inactive Bordetella pertussis. To further propose a possible key factor in drug-allergic disease interactions, we examined the inhibitory effect of NO, a marker of allergic conditions on the activities of major P450 isoforms”.
VLA COMMENT-CD RE: FLUORIDE: There may be a miniscule amount of natural fluoride that exists in the soils and is released just like other minerals. I wonder FLUORIDE being less toxic in its natural state than the much more reactive state that is in the fluoride compounds added to water. I have only seen positive effects from people drinking Fiji water – the benefits of getting rid of the aluminum are so great, and I see it as a time/toxicity equation. That a 3-6 month intensive course of Fiji water to lower the body burden of aluminum is of such benefit, that it does not need to be consumed forever to reap benefits, and there are other likely ways to protect against any miniscule fluoride exposure (like taking vitamin c and other antioxidants) that it is worth consuming it if aluminum toxicity is suspected. Our studies show that ALL people with a level of greater than 1mcg/g of dry brain weight have pathology that is associated with Alzheimer’s, or autism (depending on the age) and no brains examined with these levels were healthy. All healthy brains had less than 1 mcg of aluminum per gram of dry brain weight. It is not debatable anymore.
In addition, people with the aggressive form of MS excreted far more aluminum in their urine than healthy people, and when their aluminum body burden was reduced by drinking silica rich mineral water, they did not have any progression of their disease. The study was not designed to measure improvement in their condition, but we would have likely seen improvement if the study was designed with that outcome. A facebook group has formed called Fiji Water Detox and Epilepsy support Group and parents are reporting that their children are stopping or drastically reducing the number of seizures per day when consuming Fiji water (sometimes the kids had hundreds of seizures a day which stopped overnight when they started drinking Fiji). The benefits far outweigh any risks, and getting the aluminum out should be the highest priority for anyone dealing with a chronic, complex, inflammatory health problem.
In a nutshell, scientists all over the world have learned the following about aluminum adjuvant, most of it since 2010 (not a single one of these new discoveries or published studies was considered in Dr. Mitkus’ paper).
From Canada, 2012: “Aluminum (Al) is highly neurotoxic and has been shown to impair both prenatal and postnatal brain development in humans and experimental animals.”
From France, 2013: “However, continuously escalating doses of this poorly biodegradable adjuvant in the population may become insidiously unsafe, especially in the case of overimmunization or immature/altered blood brain barrier…”
From France, 2015: “Thus alum and other poorly biodegradable materials taken up at the periphery by phagocytes circulate in the lymphatic and blood circulation and can enter the brain using a Trojan horse mechanism similar to that used by infectious particles. Previous experiments have shown that alum administration can cause CNS dysfunction and damage, casting doubts on the exact level of alum safety.”
From France, 2016: “We conclude that Alhydrogel [aluminum adjuvant] injected at low dose in mouse muscle may selectively induce long-term Al cerebral accumulation and neurotoxic effects.”
From England, 2017: “The amount of aluminum in the brain tissue was, I would say, extraordinarily high. Very high. My group has measured the aluminum content of probably more than one hundred human brains, and these brain tissues taken from the individuals with a diagnosis of autism were some of the highest we’ve measured bar none. The only ones we’ve seen that are similar were a recent study of familial Alzheimer’s. This in itself is a very important finding.”
So, versus ten years ago, scientists now know that aluminum adjuvant, when injected, can 1) impair brain development, 2) remain in the brain much longer than thought, 3) is brought into the brain by macrophages that grab the aluminum from the vaccine injection site and recirculate it, 4) may actually be worse when injected in small doses repeatedly (like it’s done during vaccination), and 4) there’s remarkably high levels of aluminum in the brains of people diagnosed with autism.Dr. Chris Exley, the author of this most recent study (#5, and the subject of my recent article) was so moved by the results of his study he said the following:
READ MORE OF THE ABOVE comprehensive article by J.B. Handley, Co-Founder, Generation Rescue and Board Member, World Mercury Project
Table-Number-of_VAX_AL & Hg(1) link expands the table below developed by Dr. Sherri Tenpenny
The total number of mcgs of Aluminum by 18 years old is 13,538 mcgs.
Link CDC Cover up: 4,250% increase in miscarriage reports from flu shots
According to IMS Health’s Vector One: National and Total Patient Tracker Database for 2013 these are the figures for 0-1-year-olds being prescribed psychiatric drugs:
249,669 0-1 year olds are on anti-anxiety drugs (such as Xanax, Klonopin, and Ativan).
26,406 0-1 year olds are on antidepressants (such as Prozac, Zoloft, and Paxil).
There are 1,422 0-1 year olds taking ADHD drugs (such as Ritalin, Adderall, and Concerta).
654 0-1 year olds are taking antipsychotics (such as Risperdal, Seroquel, and Zyprexa).
While the CDC was correct in issuing their report on the 10,000 2-3 year olds (toddlers) being prescribed ADHD drugs, the number of toddlers on anti-anxiety and antidepressants is staggering in comparison:
318,997 2-3 year olds are on anti-anxiety drugs.
46,102 2-3 year olds are on antidepressants.
3,760 2-3 year olds are taking antipsychotics.
And as for other age groups, the numbers start in the millions with 0-5 year olds:
The total number of 0-5 year olds currently prescribed psychiatric drugs is 1,080,168.
The number of 6-12 year olds on psychiatric drugs is 4,130,340.
The number of 13-17 year olds taking psychiatric drugs is 3,617,593.
Pharmacogenetics & MASS SHOOTINGS: What is making our kids and soldiers psychotic!
Sep 1, 2017 – The group of most concern are known as the heavy metals and includes mercury, lead, cadmium, aluminium, and arsenic. The definition of what constitutes a heavy metal is vague and various criteria have been proposed based on density, atomic weight or atomic number, or various chemical properties and toxicity 1.
Not only mercury, but aluminum adjuvant is a huge problem in vaccines. It’s implicated in allergies, autism, autoimmune disorders, and Alzheimer’s. Amount of aluminum is 500mcg in Gardasil 9.
Allergy epidemic caused by vaccines (2015):
Allergens in vaccines (including milk, egg, chicken, beef, dog, latex, etc–and human DNA… long term effects have never been studied)
Aluminum+food proteins CREATE ALLERGENS IN LAB MAMMALS (for the study of allergies!), section 7 paragraphs 4 and 6
Are Vaccinations Safe for Children with Allergies? http://ow.ly/CSGA30883Yq
► AlCl3 exposure through drinking water gets close with actual chronic oral Al exposure. ► Effects of Al exposure on the hepatic microsomal protein, AND and ERND were studied. ► Metabolism of Al affected the hepatic microsomal cytochrome P450 enzyme system.
Oct 1, 2004 – Holt, shortly after, demonstrated that preformed aluminium phosphate, prepared from equimolar amounts of aluminium chloride and trisodium phosphate, acted as an adsorbant and was adjuvant active with diphtheria. Data on the use of alum
Apr 16, 2015 – Adjuvants such as the aluminum compounds (alum) have been dominantly used in many vaccines due to their immunopotentiation and safety records …. Aluminum compounds such as aluminum chloride, aluminum silicate, algammulin (gamma inulin plus AH), cesium alum (CA), Imject alum (IA) (AH plus
Using a transversely heated graphite furnace atomic absorption spectrometry to measure, for the first time, the aluminium content of brain tissue from donors with a diagnosis of autism. We have also used an aluminium-selective fluor to identify aluminium in brain tissue using fluorescence microscopy.