Tag Archives: CCHR

The Causes Mental Illness: A 61 Year History of Pharmacogenetics suppressed by Pharma

Avram Goldstein: The Founder of Molecular Pharmacology
http://molpharm.aspetjournals.org/content/83/4/720

Summary:

As the Chair of the Department of Pharmacology with responsibility for training medical students in the use of drugs, he was fascinated by the kinetics of drug action. He and his wife Dody developed the plateau principle, which emerged from the recognition that the time to steady state for any drug administered continuously or repeatedly was dependent only on its rate of elimination. These developments drove his increasing desire to see the discipline of pharmacology, both in research and in medical and graduate education, as a science with a strong mechanistic and theoretical underpinning.

Avram was present in Moscow in 1961 when Marshall Nirenberg described his elucidation of the genetic code. With these seminal developments, Avram concluded that the time was ripe for the establishment of a journal devoted to mechanistic aspects of drug action at a molecular level.

Avram was able to persuade ASPET to publish the new journal, which would be called Molecular Pharmacology. “Suitable papers are those which describe applications of the methods of biochemistry, biophysics, genetics and molecular biology to pharmacologic or toxicologic problems…”

Avram, together with his Stanford faculty colleagues Lew Aronow and Sumner Kalman, were working on Principles of Drug Action (Goldstein et al., 1968), a pharmacology textbook that was new for its time in focusing only on basic principles underlying drug action and the longer-term responses of the body to the presence of drugs.

DRUG METABOLISM RESEARCH HAS A 61 YEAR HISTORY

VLA Comment: The field of Pharmacogenomics, Pharmacogenetics, Pharmacogenomics has a 61 YEAR HISTORY  well accepted research concerning drug metabolism.  Education in this field of research has been actively suppressed by Pharma. Anonymous sources in the field of education for medical students tells us that this information is actively suppressed as the pharmacuetical industry would loose billions and billions of dollars if the public knew.  Moreso  medical students and hospital psychiatrists and doctors in general from Pediatricians ot Oconologists  have virtually no knowledge or education of drug metabolism, yet they all provide prescriptions that are contraindicated, causing Medication (drug) induced psychosis.   90% of drugs need an active and mature liver system of Cytochrome P450 enzymes to metabolize and eliminate them from an individual’s body. A substantial percentage of Caucasians, Asians, Blacks have no activity to metabolize these modern drugs.  The results – increased (apparent) psychosis.

INCREASE IN PSYCHOSIS DIAGNOSES

The increase in psychosis diagnosis is actually the agressive poisoning of humanity by uneducated doctors from the cradle to the grave.  The increase in (apparent) mental illness and special needs is due to the inability of many individuals to eliminate, from the body, modern drugs (and streets drugs) such as SSRIs vaccine excipients.

VACCINES, THE BASIS OF MENTAL ILLNESS DIAGNOSES

Vaccines contain excipients that need a mature superfamily of Cytochrome P450 in order to be metabolize and successfully eliminated from the body of infants and children. The damage done to the physiology of a one hour old infant, injected with Aluminum (which interferes in Cyp 450 metabolism in the Hep B and Vitamin K shots),  and other vaccine excipients testifies to the basic underpinnings of the epidemic in Autism, ADHD, ADD, OCD, BiPolar,neurological, mitachondrial issues, depression, anxiety, panic attacks.   The misdiagnosis of mental illness by uneducated medical professionals who extensively prescribe psychiatric drugs and the push to vaccinate, to eliminate parental choice, to eliminate vaccine waivers appears to be an organized effort to debilite the entire emerging generations of humanity through the suppression of this Pharmacogenomic knowedge.  Note: There is no mandated continuing education in drug metabolism for practicing physicans; virtually no education for medical students; yet the prescrbing of medications and the push for vaccine compliance, school shootings, homicides and suicides, special needs education, is at an all time high.

CCHR Newsletter: Overview and layman understanding of Cyp 450, Pharmacogenetics, vaccines, psyche drugs,homicide, suicide.

Below, the American Society for Pharmacology and Experimental Therapeutics chronicled the discoveries and provided communications to advance the science of drug metabolism.

The Development of Drug Metabolism Research as Expressed in the Publications of ASPET: Part 2, 1959–1983
Patrick J. Murphy College of Pharmacy and Health Sciences, Butler University, Indianapolis, Indiana Received February 18, 2008; accepted February 27, 2008

ABSTRACT (2008):
In 25 years, (now 35 years) drug metabolism research went from using subcellular
particles of undefined content to an understanding of metabolism
at the molecular level. The discoveries of cytochrome P450, en-
zyme induction, reactive intermediates, and genetic polymor-
phisms were milestones in the field. New publications from the
American Society for Pharmacology and Experimental Therapeu-
tics chronicled the discoveries and provided communications to
advance the science of drug metabolism.

THE DISCOVERY OF CYTOCHROME P450 (1957)
The discovery of P450 and its function evolved from observations by Ryan and Engel that C-21 hydroxylations of progesterone and hydroxylated progesterones were catalyzed by a CO inhibitable en-zyme in the adrenal cortex (Ryan and Engel, 1957). They character-ized the reaction as belonging to the class of enzymes categorized by
Mason as “mixed-function oxidases” (Mason, 1957) and by Hayaishias “oxygenases” (Hayaishi, 1962).

THE ROLE OF GLUTATHIONE (depleted in AUTISM?)

The role of glutathione as a precursor of mercapturic acids was confirmed in 1959 (Bray et al., 1959a,b), 80 years after the discovery of these important elimination products by Baumann and Preuss (1879). In the following 25 years, there were over 150 papers in the ASPET journals referring to aspects of glutathione in metabolism. The role of glutathione as a scavenger of reactive intermediates was ofprimary interest, as exemplified by the finding of the glutathione conjugate of acetaminophen by Hinson et al. (1982) or the formation of mercapturic acids from cyclohexene epoxide in the rat (van Bla-deren et al., 1981).

THE CAUSE of the epidemic of “apparent” mental illness: BIG PHARMA SECRET

Psychiatric Drugs, School Violence, and Big Pharma Cover-Up   by the Citizen’s Commission on Human Rights (CCHR)

DOWNLOAD PDFCCHR Newsletter-Psychiatric Drugs, School Violence, and Big Pharma Cover-Up

 VLA Comment: The powerful activist organization Citizen’s Commission on Human Rights  (CCHR), considered the most successful worldwide organization holding the reins for decades on the misuse of psychiatric drugs, appear to be having a mind melt with our powerful Vaccine Movement.  

Our Vaccine movement has also been concerned with, and focused on, the rampant misdiagnosis of mental illness foisted on  on our infants,  children and youths not only by psychiatrists but all doctors, such as pediatricians and family physians,   The resultant issuing of psyche drugs and other medications to mitigate what is, in actuality, a physiological assault of 49 vaccine doses by the age of six has been disastrous to our culture.  It is causing the disabling of the entire emerging generations of humanity.  All Drugs (prescription,  vaccine excipient, street drugs) need a mature Cytochrome P450 superfamily of liver enzymes to metabolize. This information has been known by pharmacuetical manufacturers for over 20 years.  This field is called PHARMACOGENOMICS, PHARMACOGENETICS, PHARMACOKINETICS.

It is becoming evident from the research in this field,  that the early poisoning of generations of children with vaccines containing mercury, aluminum and other vaccine excipients such as formaldehyde, ethanol, polysorbate 80 (never mind dog kidney cells, fetal tissue, contaminants, bovine serum, etc) is physiologically damaging every vaccinated child,  leading to a heirarchal range of neurological damage, depression, aggression, etc.  In an effort to mitigate generations of depressed and ill-functioning humans, the further use of psychiatric drugs is causing medication induced psychosis (DSM-5), suicidal and homicidal ideations.

The assault of vaccines; the practice of misdiagnosing generations of children as mentally ill; the prescribing of antidepressants and psyche drugs to those who do not have the cytochrome enzymes (by demographic genetics) resulting in this modern day rash of suicides, homicides, depression;  labeling such as ADD, ADHD, OCD, special needs education, has resulted in a health crisis from cradle to grave and an epidemic of school shootings by young males.

See www.SSRIStories.net   – Wake up call – read snapshots of Thousands and Thousands of personal stories of suicide and homicide of children as young as 7 years old on psychotropic drugs hanging themselves by their belt in their closet. One must remember that the suicidal and homicidal ideations are HEINOUS and compelling, unlike decisions to commit suicide by considerable reasoning.

Our mutual focus is on PHARMACOGENETICS and the failed ability to metabolize drugs and vaccine excipients.   I am so pleased and heartened, at last, to see that CCHR and our the incredibly potent Vaccine Movement are finally on the same page.

WHAT NEXT?

Our mutual mission would be well served if CCHR and our vaccine leaders, researchers, MDs, PhDs, etc. unite regarding the evidence presented by  Pharmacogenomics.  Media has pointed out the all these mass shooters are mentally ill and are on medication. What they are not aware of is that for example, 10% of Caucasians do not have the enzyme to metabolize the medications and have  “medication induced  psychosis and “heinous” ideation.

Taking a quantum leap together at this critical time in history where Donald Trump has articulated his concern about Opioids and Vaccines,  I suggest that we soon create a joint conference with CCHR and the Vaccine leaders and have conversation with experts in the field of pharmacogenetics with the goal of increasing exponentially, in harmony , our mutual momentum.

It is to be noted that several large organizations are now being vocal on the issue of Pharmacogenetics and individualized medicine such as the Mayo Clinic, St. Jude’s Hospital for Children, University of Chicago, etc. Mayo Clinic will be having a conference on Pharmacogenetics Sept. 11, 2018 in Minnesota.  I suggest many of us attend.

The easy test for your individual metabolism is available at Genesight, Genelex, etc. or at Healthscope in Australia for $250.00  The cytochrome P450 you need to look at is:

CYP 450 2D6, 2C9 and 2C19, 3A4

Or feel free to contact me at NCOWmail@gmail.com

Donald Trump on Vaccines: https://youtu.be/iP3nK0AdSHY

 

 

AMERICA’S MOST DANGEROUS PILL: KLONOPIN

deadlydrugklonopin1

It’s not Adderall or Oxy. It’s Klonopin. And doctors are doling it out like candy, causing a surge of hellish withdrawals, overdoses and deaths.

Clonazepam has wreaked such havoc on people partly because it is so highly addictive; anyone who takes it for more than a few weeks may well develop a dependence on it. As a result, you can be prescribed Klonopin as a short-term treatment for, say, insomnia, and wind up so hooked on it that you’ll begin frantically “doctor shopping” for new prescriptions if the first physician who gave it for you refuses to renew the prescription. As with all benzos, use of Klonopin for more than a month can lead to a dangerous condition known as “benzodiazepine withdrawal syndrome,” featuring elevation of a user’s heart rate and blood pressure along with insomnia, nightmares, hallucinations, anxiety, panic, weight loss, muscular spasms or cramps, and seizures.

The singer Stevie Nicks:  Nicks has described the drug as a “horrible, dangerous drug,” and said that her eventual 45-day hospital detox and rehab from the drug felt like “somebody opened up a door and pushed me into hell.” Others have described Klonopin’s effects as beginning with an energized sense of euphoria but ending up with horrifying sense of anxiety and paralysis, akin to  sticking your tongue into an electric outlet, or suddenly feeling that your brain is on fire.

Read more…