Heme oxygenase-1 regulates immune response not vaccinations

Heme oxygenase-1 regulates the immune response to influenza virus infection and vaccination in aged mice

VLA comment/Amanda: Notice the authors of the study want to add HO-1 to vaccination? They just don’t get that it is NOT vaccination that makes us healthy and by adding such an agent is potentially making sure that we develop an antibody against HO-1. That would leave us eventually dead.

HO-1 as a CRITICAL early component in innate immune response.

T-cells are controlled by HO-1?

Mice succumb to bacteria more being deficient in HO-1. HO-1 is related to a hosts resistance.

HO-1 is involved with white blood cells as well and it seems to play a role in protecting the body from macrophages.
http://bloodjournal.hematologylibrary.org/content/116/26/6054.long
http://bloodjournal.hematologylibrary.org/content/102/2/521.full
http://circres.ahajournals.org/content/100/12/1703.full

A new role for myeloid HO-1 in the innate to adaptive crosstalk and immune homeostasis.

Allergies are triggered by antibodies. HO-1 can alleviate allergies. This goes with logic, as allergies are side by side with inflammation and HO-1 is anti inflammatory.

http://rabbit.if-pan.krakow.pl/pjp/pdf/2008/6_933.pdf

HO-1 protection against Malaria. Study

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