Study: POLYMERIC NANOGELS AS VACCINE DELIVERY SYSTEM (INSTEAD OF ADJUVANTS???)
In this review, the utility of polymeric nanogels is discussed as adjuvants and protective agents for enhanced vaccination with more robust immune response and a more uniform outcome.
Vaccines may include synthetic peptides representing an
epitope of a pathogen protein; a full-length protein carrying
several epitopes that may be recognizable by B and T cells,
produced either by pathogens, synthetically or recombinantly; or
a gene encoding a particular protein fused into a DNA or RNA
…preparations of total mRNA isolated directly
from tumors may also be used.
Some of the currently explored nanoparticles are metallic nanoparticles, mesoporous silica nanoparticles, carbonbased nanoparticles, and polymer nanogels. READ ARTICLE