Depression is on the rise around the world and, according to one author, the World Health Organization (WHO) has stated that approximately 300 million people worldwide suffer from this debilitating disorder
Author, Amy Morin, LCSW, wrote in her article, Depression Statistics Everyone Should Know, that in the United States alone, 16.2 million adults have experienced a major depressive episode in the past year.
Dr.Kelly Brogan’s paper outlined the strong possibility that the aluminum adjuvant that is currently being used in at least 18 childhood vaccinations may be responsible for the increase in long-term brain inflammation, neurological complications and autoimmunity. She stated that:
“One of the most relevant aluminum-containing vaccines is Gardasil, responsible for more than 34000 reported adverse events,and now Gardasil 9, which contains twice the aluminum dose (ie, now with 500 μg per 3 recommended doses).”
The Pandemic of Iatrogenocide, Associated with Drug and Vaccine Poisoning Causing Mitochondrial and DNA Disruption.
DR. GARY KOHL…READ ARTICLE
“Mitochondrial damage is now understood to play a role in a wide range of seemingly unrelated disorders such as schizophrenia, diabetes, Parkinson’s disease, chronic fatigue syndrome, and nonalcoholic steatohepatitis. Recently it has become known that iatrogenic (physician or treatment-caused) mitochondrial damage explains many adverse reactions from medications.” — John Neustadt, MD and Steven Pieczenik, MD
VLA COMMENT: And Autism, vaccine induced mitochondria damage underlying Autism
“All classes of psychotropic drugs have been documented to damage mitochondria, as have statin medications, analgesics such as acetaminophen, and many others.” – John Neustadt, MD and Steven Pieczenik, MD
Near infrared radiation rescues mitochondrial dysfunction in cortical neurons after oxygen-glucose deprivation
EXCERPTS: They raised troubling questions about some vaccine ingredients’ documented impact on reproduction, cited serious deficiencies (some would say criminal negligence) in preliminary vaccine trials and concluded that further research was “urgently required….for the purposes of population health and public vaccine confidence.”
Approximately 60% of women who did not receive the HPV vaccine had been pregnant at least once compared to just 35% of women who had had an HPV shot had ever conceived.
For married women, the gap was also about 25%: 75% who did not receive the shot were found to have conceived, while only 50% who received the vaccine had ever been pregnant.
“Results suggest that females who received the HPV shot were less likely to have ever been pregnant than women in the same age group who did not receive the shot,” the study says.
Kaiser and another care provider (the 6 VSD organizations collaborating on this paper) found greater than 900 possible spontaneous abortion records associated with the flu vaccine for pregnant women. Yet a search of VAERS using an approximation of their parameters from their supplemental tables #1 Supplemental file for the manuscript failed to find any spontaneous abortions from the healthcare providers in the states these organizations serve in the flu seasons (2010-11 and 2011-2012).
So it appears that these major providers are not reporting to VAERS as they are required to do by law. The study, however, does not break down the SAs per flu season.
Supplementary Table 1 #1 Supplemental file for the manuscript
What this means:
# 1 Kaiser & Kaiser associated care providers are not reporting to VAERS so that the public does not know what is going and researchers have invalid data. Kaiser, etc. are reporting to their own VSD data bank >900 SAs in two seasons and not a one is reported in VAERS during the same time period.
#2 We can actually calculate and define by this study “how under-reported VAERS is”
#3 Consider the harm to the public (pregnant) women when the real miscarriage data is hidden.
#4 Consider that the PREP act states that everyone must be adjudicated by the Vaccine Court with the exception that a lawsuit can commence to entities outside the Vaccine Court if there is “willful misconduct”
#5 The Goldman HET study covered three seasons: 2008/9, 2009/10, 2010/11 Off hand we see that there is a disconnect between our research data from VAERS in 2010/11 and the data from VSD. The supplements will help us pin point the SAs in 2010/11, so we can see the disparity.
#6 VLA COMMENT: Between Kaiser Permante data (VSD) collection reporting fetal deaths from the flu shot 900X more than VAERS while VAERS had 0 reports, what does that say for the accuracy and reliability of independent researchers using VAERS as source. VSD is unavailable to independent researchers. One thing President Trump might do with the Independent Vaccine Science and Safety Commision is to allow Independent researchers to access the KAISER DATA since the CDC pays for it with Taxpayer dollars.
Avram Goldstein: The Founder of Molecular Pharmacology
As the Chair of the Department of Pharmacology with responsibility for training medical students in the use of drugs, he was fascinated by the kinetics of drug action. He and his wife Dody developed the plateau principle, which emerged from the recognition that the time to steady state for any drug administered continuously or repeatedly was dependent only on its rate of elimination. These developments drove his increasing desire to see the discipline of pharmacology, both in research and in medical and graduate education, as a science with a strong mechanistic and theoretical underpinning.
Avram was present in Moscow in 1961 when Marshall Nirenberg described his elucidation of the genetic code. With these seminal developments, Avram concluded that the time was ripe for the establishment of a journal devoted to mechanistic aspects of drug action at a molecular level.
Avram was able to persuade ASPET to publish the new journal, which would be called Molecular Pharmacology. “Suitable papers are those which describe applications of the methods of biochemistry, biophysics, genetics and molecular biology to pharmacologic or toxicologic problems…”
Avram, together with his Stanford faculty colleagues Lew Aronow and Sumner Kalman, were working on Principles of Drug Action (Goldstein et al., 1968), a pharmacology textbook that was new for its time in focusing only on basic principles underlying drug action and the longer-term responses of the body to the presence of drugs.
DRUG METABOLISM RESEARCH HAS A 61 YEAR HISTORY
VLA Comment: The field of Pharmacogenomics, Pharmacogenetics, Pharmacogenomics has a 61 YEAR HISTORY well accepted research concerning drug metabolism. Education in this field of research has been actively suppressed by Pharma. Anonymous sources in the field of education for medical students tells us that this information is actively suppressed as the pharmacuetical industry would loose billions and billions of dollars if the public knew. Moreso medical students and hospital psychiatrists and doctors in general from Pediatricians ot Oconologists have virtually no knowledge or education of drug metabolism, yet they all provide prescriptions that are contraindicated, causing Medication (drug) induced psychosis. 90% of drugs need an active and mature liver system of Cytochrome P450 enzymes to metabolize and eliminate them from an individual’s body. A substantial percentage of Caucasians, Asians, Blacks have no activity to metabolize these modern drugs. The results – increased (apparent) psychosis.
INCREASE IN PSYCHOSIS DIAGNOSES
The increase in psychosis diagnosis is actually the agressive poisoning of humanity by uneducated doctors from the cradle to the grave. The increase in (apparent) mental illness and special needs is due to the inability of many individuals to eliminate, from the body, modern drugs (and streets drugs) such as SSRIs vaccine excipients.
VACCINES, THE BASIS OF MENTAL ILLNESS DIAGNOSES
Vaccines contain excipients that need a mature superfamily of Cytochrome P450 in order to be metabolize and successfully eliminated from the body of infants and children. The damage done to the physiology of a one hour old infant, injected with Aluminum (which interferes in Cyp 450 metabolism in the Hep B and Vitamin K shots), and other vaccine excipients testifies to the basic underpinnings of the epidemic in Autism, ADHD, ADD, OCD, BiPolar,neurological, mitachondrial issues, depression, anxiety, panic attacks. The misdiagnosis of mental illness by uneducated medical professionals who extensively prescribe psychiatric drugs and the push to vaccinate, to eliminate parental choice, to eliminate vaccine waivers appears to be an organized effort to debilite the entire emerging generations of humanity through the suppression of this Pharmacogenomic knowedge. Note: There is no mandated continuing education in drug metabolism for practicing physicans; virtually no education for medical students; yet the prescrbing of medications and the push for vaccine compliance, school shootings, homicides and suicides, special needs education, is at an all time high.
CCHR Newsletter: Overview and layman understanding of Cyp 450, Pharmacogenetics, vaccines, psyche drugs,homicide, suicide.
Below, the American Society for Pharmacology and Experimental Therapeutics chronicled the discoveries and provided communications to advance the science of drug metabolism.
The Development of Drug Metabolism Research as Expressed in the Publications of ASPET: Part 2, 1959–1983
Patrick J. Murphy College of Pharmacy and Health Sciences, Butler University, Indianapolis, Indiana Received February 18, 2008; accepted February 27, 2008
In 25 years, (now 35 years) drug metabolism research went from using subcellular
particles of undefined content to an understanding of metabolism
at the molecular level. The discoveries of cytochrome P450, en-
zyme induction, reactive intermediates, and genetic polymor-
phisms were milestones in the field. New publications from the
American Society for Pharmacology and Experimental Therapeu-
tics chronicled the discoveries and provided communications to
advance the science of drug metabolism.
THE DISCOVERY OF CYTOCHROME P450 (1957)
The discovery of P450 and its function evolved from observations by Ryan and Engel that C-21 hydroxylations of progesterone and hydroxylated progesterones were catalyzed by a CO inhibitable en-zyme in the adrenal cortex (Ryan and Engel, 1957). They character-ized the reaction as belonging to the class of enzymes categorized by
Mason as “mixed-function oxidases” (Mason, 1957) and by Hayaishias “oxygenases” (Hayaishi, 1962).
THE ROLE OF GLUTATHIONE (depleted in AUTISM?)
The role of glutathione as a precursor of mercapturic acids was confirmed in 1959 (Bray et al., 1959a,b), 80 years after the discovery of these important elimination products by Baumann and Preuss (1879). In the following 25 years, there were over 150 papers in the ASPET journals referring to aspects of glutathione in metabolism. The role of glutathione as a scavenger of reactive intermediates was ofprimary interest, as exemplified by the finding of the glutathione conjugate of acetaminophen by Hinson et al. (1982) or the formation of mercapturic acids from cyclohexene epoxide in the rat (van Bla-deren et al., 1981).
According to Mayo Clinic “generally, these antidepressants are an option during pregnancy:”
VLA comment: The list below are the recommended options that however come with risks. What is not listed are the rest of the pharma madness drugs given to women approaching child bearing age and therefore compelled to continue the regimen during pregancy. Other drugs are not listed because they are so risky for birth defects that they are not even considered. However, how many young women have been prescribed these medication since teenagers?
- Certain selective serotonin reuptake inhibitors (SSRIs). SSRIs are generally considered an option during pregnancy, including citalopram (Celexa), fluoxetine (Prozac) and sertraline (Zoloft). Potential complications include an increased risk of heavy bleeding after giving birth (postpartum hemorrhage), premature birth and low birth weight. Most studies show that SSRIs aren’t associated with birth defects. However, paroxetine (Paxil) appears to be associated with a small increased risk of a fetal heart defect.
- Serotonin and norepinephrine reuptake inhibitors (SNRIs). SNRIs also are considered an option during pregnancy, including duloxetine (Cymbalta) and venlafaxine (Effexor XR). However, research suggests that taking SNRIs at the end of pregnancy is associated with postpartum hemorrhage.
- Bupropion (Wellbutrin). This medication is used for both depression and smoking cessation. Although bupropion isn’t generally considered a first line treatment for depression during pregnancy, it might be an option for women who haven’t responded to other medications. Research suggests taking bupropion during pregnancy might be associated with heart defects.
- Tricyclic antidepressants. This class of medications includes nortriptyline (Pamelor). Although tricyclic antidepressants aren’t generally considered a first line or second line treatment, they might be an option for women who haven’t responded to other medications. The tricyclic antidepressant clomipramine might be associated with fetal birth defects, including heart defects. Use of these medications during the second or third trimester might also be linked with postpartum hemorrhage. READMore
Electroshock is also known by the euphemism electroconvulsive therapy or ECT. Many electroshock patients receive the treatment against their will. Psychiatrists also claim that electroshock is safe during pregnancy and give the treatment to pregnant women.
Electroconvulsive therapy is a safe and effective treatment during pregnancy and of particular benefit in the acute treatment of suicidal ideation.
VLA COMMENT: Suicidal ideations are a result of anti depressants and other drugs not being metabolized properly. These drugs need Cytochrome P450 to metabolize. If the patient does not have the activity of this family of liver enzymes and are prescribed drugs that are contra-indicated, as per the package inserts, adverse reactions such as “compelling” suicideal ideations (and heinous ideations of homicide) are likely to occur.
As the statement above refers to “acute treatment of suicidal ideation” it signals that the pregnant patient may be on medication that cannot be metabolized by his/her system of liver enzymes. Hence…the apparent solution to pregnant women who have been on anti depressants and psyche drugs for years and must continue during pregancy, is to top it all off with SHOCK TREATMENTS. This allows the women to remain on psyche drug medication during her pregnancy. However as noted in our posting Glyphosate, Drugs and Vaccines....the Cytochrome P450 metabolism is also found in the placenta.
Washington University in St. Louis Shocks Pregnant Women
According to the Citizen’s Commission on Human Rights (CCHR), Approximately 150,000 people get ECT every year in the US, with 2,000 shock treatments being done every year by WUSTL psychiatrists at Barnes-Jewish Hospital. Complications after treatment usually increase with the age of the patient; small surprise there. WUSTL psychiatrists say that, “ECT is considered a safe treatment modality in pregnant women in whom a number of medications may be associated with risk to the fetus.” READ MORE…
Article: ELECTRO SHOCK THERAPY WHILE PREGNANT
CCHR Newsletter: Overview of Cyp 450, Pharmacogenetics, Psyche Drugs, vaccines.
Read Study glyphosate_rats_CYP_enzyme_suppression_2006
Syngenta Patent shows that the Genetic Engineering of our nations food supply is based on Cytochrome P450 technology whereby the genetically engineered seed is manipulated to be an ultra rapidmetabolizer while the “weeds” who are normal metabolizer dies in the presence of Glysophate. Cytochrome P450 Gene Conferring herbicide resistance PATENT
MENTAL ILLNESS DIAGNOSIS –
PHARMA DRUGS, STREET DRUGS & MEDICATION AND METABOLIZING OPIOIDS
Plants and humans share the same detox mechanism involving Cytochrome P450. In humans Cytocrome P450
90% of today’s modern drugs are metabolized by Cytochrome P450.
CYP1A2, CYP2C9, CYP2C19, CYP2D6, CYP3A4, and CYP3A5 enzymes metabolize 90 percent of drugs. these enzymes are predominantly expressed in the liver, but they also occur in the small intestine (reducing drug bioavailability), lungs, placenta, and kidneys.2
One out of every 15 white or black persons may have an exaggerated response to standard doses of beta blockers (e.g., metoprolol [Lopressor]), or no response to the analgesic tramadol (Ultram). This is because drug metabolism via CYP450 enzymes exhibits genetic variability (polymorphism) that influences a patient’s response to a particular drug.3
Every person inherits one genetic allele from each parent. Alleles are referred to as “wild type” or “variant,” with wild type occurring most commonly in the general population.
For example, 7 percent of white persons and 2 to 7 percent of black persons are poor metabolizers of drugs dependent on CYP2D6, which metabolizes many beta blockers, antidepressants, and opioids.7,8 One in five Asian persons is a poor metabolizer of drugs dependent on CYP2C19, which metabolizes phenytoin (Dilantin), phenobarbital, omeprazole (Prilosec), and other drugs.9
The Effect of Cytochrome P450
Metabolism on Drug Response,
Interactions, and Adverse Effects READ STUDYCyp Study
Studies: Cytochrome P450 and failure of infants to metabolize vaccine excipients READ more…
Early Childhood Vaccines contain excipients that need Cytochrome P450 to metabolize.
VLA Comment: Cytochrome P450 is not mature in infants and children under the age of three years old yet we are giving vaccines with excipients that must be detoxed out of the body by Cytochrome P450 family of liver enzymes which infants do not have. These enzymes are predominantly expressed in the liver, but they also occur in the small intestine (reducing drug bioavailability), lungs, placenta, and kidneys.2
Note in cases of Autism and vaccinating pregnant women:
Cyp 450 are found in the “Small intestines and placenta”
Tucker is touching on every male crisis that is would be covered by two major causal issues:
Autism rates are gender biased: Various studies, together with anecdotal evidence have come up with men/women ratios ranging from 2:1 to 16:1.
Toxic Agriculture: Atrazine, Alachlor, DDT, Round Up MALE SPERM COUNT DOWN 50%
ARE ENVIRONMENTAL CHEMICALS CAUSING MEN TO LOSE THEIR FUNDAMENTAL MASCULINITY?
The hypothesis put forth in THE LANCET suggests that males are being exposed in the womb to female sex hormones that permanently alter their sexual development, increase their risk of having undescended testicles, hypospadias, and testicular cancer, and reduce by half the average man’s ability to produce sperm.
VLA COMMENT: RACHEL’S HAZARDOUS WASTE NEWS HAS BEEN FOCUSING ON THE EFFECT OF TOXIC AGRICULTURE ON MALE SPERM COUNT. IT HAS MANY STUDIES ON THE SUBJECT SEARCH NEWSLETTER
News and resources for environmental justice.
Temporal trends in sperm count: a systematic review and meta-regression analysis
This comprehensive meta-regression analysis reports a significant decline in sperm counts (as measured by SC and TSC) between 1973 and 2011, driven by a 50–60% decline among men unselected by fertility from North America, Europe, Australia and New Zealand. Because of the significant public health implications of these results, research on the causes of this continuing decline is urgently needed. READ STUDY…