The field of pharmacogenomics and pharmacogenetics provides a promising science base for vaccine research and development. A broad range of phenotype/genotype data combined with high-throughput genetic sequencing and bioinformatics are increasingly being integrated into this emerging field of vaccinomics. This paper discusses the hypothesis of the ‘immune response gene network’ and genetic (and bioinformatic) strategies to study associations between immune response gene polymorphisms and variations in humoral and cellular immune responses to prophylactic viral vaccines, such as measles–mumps–rubella, influenza, HIV, hepatitis B and smallpox. Immunogenetic studies reveal promising new vaccine targets by providing a better understanding of the mechanisms by which gene polymorphisms may influence innate and adaptive immune responses to vaccines, including vaccine failure and vaccine-associated adverse events. Additional benefits from vaccinomic studies include the development of personalized vaccines, the development of novel vaccines and the development of novel vaccine adjuvants.
As one clinician noted, ‘…vaccines licensed in the USA are safe and effective. However, not every vaccine is equally safe or equally effective in every person’ .
Welcome to the Australian state of Victoria, where the minister of health, Jill Hennessy, has just put all doctors under the gun. There are currently 41 vaccinations administered to children in Australia between birth and 4 years of age – more if you are of Aboriginal or Torres-Strait Islander descent.
Vaccinating every child has become so important to Hennessey, she’s declared that a doctor who writes an exemption will be ignored. In fact, that doctor, by implication, will be considered “rogue.”
He could have his license to practice stripped. He could be prosecuted. He could be denied a way to earn a living.
Instead, in order to allow a child an exemption from taking vaccines, evidence must be shown from some sort of medical registry. How this system will work is not clear.
Using a transversely heated graphite furnace atomic absorption spectrometry to measure, for the first time, the aluminium content of brain tissue from donors with a diagnosis of autism. We have also used an aluminium-selective fluor to identify aluminium in brain tissue using fluorescence microscopy.
We recorded some of the highest values for brain aluminium content ever measured
in healthy or diseased tissues in these male ASDdonors including values of 17.10, 18.57 and 22.11 g/g dry wt. (Table 1)
Developmental Pharmacokinetics in Pediatric Populations
Hong Lu, PhD and Sara Rosenbaum, PhD
Department of Biomedical and Pharmaceutical Sciences, University of Rhode Island, Kingston, Rhode Island
Information on drug absorption and disposition in infants and children has increased considerably over the past 2 decades. However, the impact of specific age-related effects on pharmacokinetics, pharmacodynamics, and dose requirements remains poorly understood. Absorption can be affected by the differences in gastric pH and stomach emptying time that have been observed in the pediatric population. Low plasma protein
concentrations and a higher body water composition can change drug distribution. Metabolic processes are often immature at birth, which can lead to a reduced clearance and a prolonged half-life for those drugs for which metabolism is a significant mechanism for elimination. Renal excretion is also reduced in neonates due to immature glomerular filtration, tubular secretion, and reabsorption. Limited data are available on the pharmacodynamic behavior of drugs in the pediatric population.Pediatric Population study Cyp 450.
VLA Comment: Remember children under 3 years old have “immature” cytochrome P450 and 10% of Caucasians for example, are “non-metabolizers”…they cannot metablize many drugs all their lives and become psychotic when given drugs after being diagnosed as ADHD, Autism, etc which are vaccine injuries caused by inability to metabolize the ingredients in vaccines.
Some more books (see recommended books in our list to the right)
“Vaccination Policy and the U.K. Government:
the Untold Truth” by England & Tomljenovich
“Vaccination Voodoo: What YOU Don’t Know
About Vaccines” by Frompovich & King
“The Book On Greatness: How to Keep Shining
Your Light by Mary Pulles Cavanaugh
“Eat to Beat Disease: Foods Medicinal
Qualities” by Catherine J. Frompovich
“No Vaccines for Me!”, a family friendly
book by Kathleen Dunkelberger
“Save My Species” by Freddie the Chihuahua
(due to be published by the end of 2017)
Leaving a lucrative career as a nephrologist (kidney doctor), Dr. Suzanne Humphries is now free to actually help cure people. In this autobiography she explains why good doctors are constrained within the current corrupt medical system from practicing real, ethical medicine. FREE Shipping Available! Order here.
Harvard Immunologist to Legislators: Unvaccinated Children Pose ZERO Risk to Anyone
OPEN LETTER TO LEGISLATORS
My name is Tetyana Obukhanych. I hold a PhD in Immunology. I am writing this letter in the hope that it will correct several common misperceptions about vaccines in order to help you formulate a fair and balanced understanding that is supported by accepted vaccine theory and new scientific findings.
Do unvaccinated children pose a higher threat to the public than the vaccinated?
It is often stated that those who choose not to vaccinate their children for reasons of conscience endanger the rest of the public, and this is the rationale behind most of the legislation to end vaccine exemptions currently being considered by federal and state legislators country-wide.
You should be aware that the nature of protection afforded by many modern vaccines – and that includes most of the vaccines recommended by the CDC for children – is not consistent with such a statement. READ MORE… INCLUDES LIST OF VACCINES THAT DO NOT PROTECT THE PUBLIC.
There are woollier claims about what’s been going on at t
secretive bioweapons laboratory on Plum Island for the past 60 years but I’ll cover those at another time, so as not to taint the pristine chain of evidence presented here that establishes the origins of the modern day Lyme disease epidemic in the US.
If you look on a map at the distribution of Lyme disease, you’ll find that the epidemiological “bullseye” is Plum Island, an 840- acre glacial moraine off the northeastern tip of Long Island, New York and just 9 miles from the Connecticut shore. Since 1956, Plum Island has been the site of a secretive USDA Animal Disease Center that is off-limits to the public.
Lyme disease–carrying ticks are now in half of all U.S. counties
The ticks that transmit Lyme disease, a debilitating flulike illness caused by Borrelia bacteria, are spreading rapidly across the United States. A new study shows just how rapidly. Over the past 20 years, the two species known to spread the disease to humans have together advanced into half of all the counties in the United States.
Lyme disease cases have tripled in the United States over the last 2 decades, making it the most commonly reported vector-borne disease in the Northern Hemisphere. The disease now affects around 300,000 Americans each year. If diagnosed early—a rash commonly appears around the site of the tick bite—Lyme can be effectively treated with antibiotics, but longer term infections can produce more serious symptoms, including joint stiffness, brain inflammation, and nerve pain.
Study finds association between childhood vaccination and the onset of neuropsychiatric disorders
There was a particularly strong link between vaccination and the eating disorder anorexia nervosa within 3 months of getting the shot. Influenza vaccinations were also found to be linked with the neuropsychiatry conditions of OCD, anorexia nervosa and anxiety disorders when they were administered within 3 to 12 months of the diagnosis. READ MORE…