Dr Kohls is a retired physician who practiced holistic mental health care for the last decade of his career. Virtually all of his patients exhibited iatrogenic (prescription drug-related) syndromes such as are mentioned in the article above. In retrospect, those patients were actually manifesting iatrogenic mitochondrial diseases.
“Mitochondrial damage is now understood to play a role in a wide range of seemingly unrelated disorders such as schizophrenia, diabetes, Parkinson’s disease, chronic fatigue syndrome, and nonalcoholic steatohepatitis. Recently it has become known that iatrogenic (physician or treatment-caused) mitochondrial damage explains many adverse reactions from medications. All classes of psychotropic drugs have been documented to damage mitochondria, as have statin medications, analgesics such as acetaminophen, and many others.”— John Neustadt, MD and Steven Pieczenik, MD
1) Aluminum-induced Defective Mitochondrial Metabolism Perturbs Cytoskeletal Dynamics in Human Astrocytoma Cells.
2) Thimerosal-Derived Ethylmercury Is a Mitochondrial Toxin in Human Astrocytes
3) Medication-induced Mitochondrial Damage and Disease
Acquired Conditions in which Mitochondrial Dysfunction has been Implicated (as of 2007)
Diabetes
Huntington’s disease
Cancer including hepatitis-C virus-associated hepatocarcinogenesis
Alzheimer disease
Parkinson’s disease
Bipolar disorder
Schizophrenia
Aging and senescence
Anxiety disorders
Nonalcoholic steatohepatitis (NASH – late stage of nonalcoholic fatty infiltration of the liver)
Cardiovascular disease, including atherosclerosis
Sarcopenia (muscle-wasting disease, mainly of the elderly)
Exercise intolerance
Fatigue, including chronic fatigue syndrome, fibromyalgia, and myofascial pain
<<snip>>
Medications Documented to Induce Mitochondrial Damage (as of 2007)
http://psychrights.org/research/Digest/NLPs/DrugsCauseMitochondrialDamage.PDF
Alcoholism medications Ex: Antabuse
Alzheimer’s dementia drugs Ex: Tacrine (Cognex), Galantamine
Analgesics (for pain) and anti-inflammatory drugs, Ex: Aspirin, acetaminophen (Tylenol), indomethacin, Naproxen
Anesthetics Ex: lidocaine, propofol (also general anesthetics like halothane. isoflurane, sevoflurane)
Angina medications Ex: amiodarone
Antiarrhythmic (regulates heartbeat) Ex: amiodarone (also beta blockers)
Antibiotics Ex: tetracycline (also chloramphenicol, Cipro)
Antidepressants Ex: amitriptyline, citalopram (Celexa), fluoxetine (Prozac, Symbyax, Sarafem)
Antipsychotics Ex: chlorpromazine, fluphenazine, haloperidol, risperidone, quetiapine, clozapine, olanzapine
Anxiety medications Ex:(Every benzodiazepine), including alprazolam (Xanax), diazepam (valium)
Barbiturates Ex: amobarbital, phenobarbital, pentobarbital, , propofol, secobarbital
Cholesterol-lowering medications Ex: All statins – atorvastatin, fluvastatin, lovastatin, pravastatin, rosuvastatin (Crestor), simvastatin, cholestyramine, clofibrate (Atromid-S)
Cancer (chemotherapy) medications Ex: Mitomycin C, profiromycin, adriamycin
Diabetes medications Ex: metformin, Glucophage, troglitazone, rosiglitazone, buformin
HIV/AIDS medications Ex: (AZT, zidovudine)
Epilepsy/Seizure medications Ex: valproic acid (Depakene, depakote, divalproex sodium)
Mood stabilizers Ex: lithium
Parkinson’s disease medications
Vaccine Ingredients Ex: Mercury, aluminum, ethylene glycol
