Temporal Association of Certain Neuropsychiatric Disorders Following Vaccination of Children and Adolescents: A Pilot Case-Control Study
This study examines whether antecedent vaccinations are associated with increased incidence of obsessive-compulsive disorder (OCD), anorexia nervosa (AN), anxiety disorder, chronic tic disorder, attention deficit hyperactivity disorder, major depressive disorder, and bipolar disorder in a national sample of privately insured children
Subjects with newly diagnosed AN were more likely than controls to have had any vaccination in the previous 3 months [hazard ratio (HR) 1.80, 95% confidence interval 1.21-2.68]. Influenza vaccinations during the prior 3, 6, and 12 months were also associated with incident diagnoses of AN, OCD, and an anxiety disorder. Several other associations were also significant with HRs greater than 1.40 (hepatitis A with OCD and AN; hepatitis B with AN; and meningitis with AN and chronic tic disorder).
CONCLUSION:
This pilot epidemiologic analysis implies that the onset of some neuropsychiatric disorders may be temporally related to prior vaccinations in a subset of individuals
As of September 2017, a total of 58 studies have investigated the relationship between fluoride and human intelligence, and over 40 studies have investigated the relationship fluoride and learning/memory in animals. Of these investigations, 51 of the 58 human studies have found that elevated fluoride exposure is associated with reduced IQ, while 45 animal studies have found that fluoride exposure impairs the learning and/or memory capacity of animals. The human studies, which are based on IQ examinations of over 12,000 children, provide compelling evidence that fluoride exposure during the early years of life can damage a child’s developing brain.
In a nutshell, scientists all over the world have learned the following about aluminum adjuvant, most of it since 2010 (not a single one of these new discoveries or published studies was considered in Dr. Mitkus’ paper).
From Canada, 2012: “Aluminum (Al) is highly neurotoxic and has been shown to impair both prenatal and postnatal brain development in humans and experimental animals.” From France, 2013: “However, continuously escalating doses of this poorly biodegradable adjuvant in the population may become insidiously unsafe, especially in the case of overimmunization or immature/altered blood brain barrier…” From France, 2015: “Thus alum and other poorly biodegradable materials taken up at the periphery by phagocytes circulate in the lymphatic and blood circulation and can enter the brain using a Trojan horse mechanism similar to that used by infectious particles. Previous experiments have shown that alum administration can cause CNS dysfunction and damage, casting doubts on the exact level of alum safety.” From France, 2016: “We conclude that Alhydrogel [aluminum adjuvant] injected at low dose in mouse muscle may selectively induce long-term Al cerebral accumulation and neurotoxic effects.” From England, 2017: “The amount of aluminum in the brain tissue was, I would say, extraordinarily high. Very high. My group has measured the aluminum content of probably more than one hundred human brains, and these brain tissues taken from the individuals with a diagnosis of autism were some of the highest we’ve measured bar none. The only ones we’ve seen that are similar were a recent study of familial Alzheimer’s. This in itself is a very important finding.”
So, versus ten years ago, scientists now know that aluminum adjuvant, when injected, can 1) impair brain development, 2) remain in the brain much longer than thought, 3) is brought into the brain by macrophages that grab the aluminum from the vaccine injection site and recirculate it, 4) may actually be worse when injected in small doses repeatedly (like it’s done during vaccination), and 4) there’s remarkably high levels of aluminum in the brains of people diagnosed with autism.Dr. Chris Exley, the author of this most recent study (#5, and the subject of my recent article) was so moved by the results of his study he said the following:
The total number of mcgs of Aluminum by 18 years old is 13,538 mcgs.
VLA Comment:These researchers and other moral saviors behind the scenes of public awareness (CD, CB, PK, GG, MDG, Cong B, Cong P…on and on) are the same dedicated persons who blew the whistle on Mercury in vaccines and dental fillings. Most mercury was taken out of vaccines in 2001. At one time mercury was in 16 vaccine doses, debilitating our children, causing them to be diagnosed as “mentally ill”, OCD, Bipolar, ADHD, Autism; prescribed psychiatric drugs as young a 0-1 years old.However, Mercury is still in vaccines today (see chart above).
Mercury and aluminum are both ” heavy metals”. Heavy Metals are causing malfunction; electrical malfunction, immune dysfunction, digestive disorder in every incoming generation of humanity. Metals do not belong in the human physiology. Adults are now spending thousands of dollars trying to get heavy metals out of their systems. Where do you think these deposits came from? If heavy metals negatively affect the outer environment it would be common sense to conclude that they would be harmful to the inner environment of man…and especially dangerous our young children and pregnant moms.
Link CDC Cover up: 4,250% increase in miscarriage reports from flu shots
According to IMS Health’s Vector One: National and Total Patient Tracker Database for 2013 these are the figures for 0-1-year-olds being prescribed psychiatric drugs:
249,669 0-1 year olds are on anti-anxiety drugs (such as Xanax, Klonopin, and Ativan).
26,406 0-1 year olds are on antidepressants (such as Prozac, Zoloft, and Paxil).
There are 1,422 0-1 year olds taking ADHD drugs (such as Ritalin, Adderall, and Concerta).
654 0-1 year olds are taking antipsychotics (such as Risperdal, Seroquel, and Zyprexa).
While the CDC was correct in issuing their report on the 10,000 2-3 year olds (toddlers) being prescribed ADHD drugs, the number of toddlers on anti-anxiety and antidepressants is staggering in comparison:
318,997 2-3 year olds are on anti-anxiety drugs.
46,102 2-3 year olds are on antidepressants.
3,760 2-3 year olds are taking antipsychotics.
And as for other age groups, the numbers start in the millions with 0-5 year olds:
The total number of 0-5 year olds currently prescribed psychiatric drugs is 1,080,168.
The number of 6-12 year olds on psychiatric drugs is 4,130,340.
The number of 13-17 year olds taking psychiatric drugs is 3,617,593.[3]
Sep 1, 2017 – The group of most concern are known as the heavy metals and includes mercury, lead, cadmium, aluminium, and arsenic. The definition of what constitutes a heavy metal is vague and various criteria have been proposed based on density, atomic weight or atomic number, or various chemical properties and toxicity 1.
Not only mercury, but aluminum adjuvant is a huge problem in vaccines. It’s implicated in allergies, autism, autoimmune disorders, and Alzheimer’s. Amount of aluminum is 500mcg in Gardasil 9.
Aluminum levels in autistic brains “extraordinarily high”:
The various factors that impact pharmacokinetics and pharmacodynamics mature towards adult values at different rates, thus requiring continual modification of drug dose regimens in neonates, infants, and children.
The results revealed that exposure to AlCl3 inhibited the microsomal CYP450 dependent enzyme system of liver. Our findings suggest that long term daily exposure of AlCl3 exerts the suppressive effects and thus may cause dysfunction of hepatic CYP450 dependent enzyme system of rat.
Highlights
► AlCl3 exposure through drinking water gets close with actual chronic oral Al exposure. ► Effects of Al exposure on the hepatic microsomal protein, AND and ERND were studied. ► Metabolism of Al affected the hepatic microsomal cytochrome P450 enzyme system.
Oct 1, 2004 – Holt, shortly after, demonstrated that preformed aluminium phosphate, prepared from equimolar amounts of aluminium chloride and trisodium phosphate, acted as an adsorbant and was adjuvant active with diphtheria. Data on the use of alum-precipitated vaccines can be found in older literature, but in …
Apr 16, 2015 – Adjuvants such as the aluminum compounds (alum) have been dominantly used in many vaccines due to their immunopotentiation and safety records …. Aluminum compounds such as aluminum chloride, aluminum silicate, algammulin (gamma inulin plus AH), cesium alum (CA), Imject alum (IA) (AH plus ..
The field of pharmacogenomics and pharmacogenetics provides a promising science base for vaccine research and development. A broad range of phenotype/genotype data combined with high-throughput genetic sequencing and bioinformatics are increasingly being integrated into this emerging field of vaccinomics. This paper discusses the hypothesis of the ‘immune response gene network’ and genetic (and bioinformatic) strategies to study associations between immune response gene polymorphisms and variations in humoral and cellular immune responses to prophylactic viral vaccines, such as measles–mumps–rubella, influenza, HIV, hepatitis B and smallpox. Immunogenetic studies reveal promising new vaccine targets by providing a better understanding of the mechanisms by which gene polymorphisms may influence innate and adaptive immune responses to vaccines, including vaccine failure and vaccine-associated adverse events. Additional benefits from vaccinomic studies include the development of personalized vaccines, the development of novel vaccines and the development of novel vaccine adjuvants.
As one clinician noted, ‘…vaccines licensed in the USA are safe and effective. However, not every vaccine is equally safe or equally effective in every person’ [2].
Using a transversely heated graphite furnace atomic absorption spectrometry to measure, for the first time, the aluminium content of brain tissue from donors with a diagnosis of autism. We have also used an aluminium-selective fluor to identify aluminium in brain tissue using fluorescence microscopy.
We recorded some of the highest values for brain aluminium content ever measured
in healthy or diseased tissues in these male ASDdonors including values of 17.10, 18.57 and 22.11 g/g dry wt. (Table 1)
Developmental Pharmacokinetics in Pediatric Populations
Hong Lu, PhD and Sara Rosenbaum, PhD
Department of Biomedical and Pharmaceutical Sciences, University of Rhode Island, Kingston, Rhode Island
Information on drug absorption and disposition in infants and children has increased considerably over the past 2 decades. However, the impact of specific age-related effects on pharmacokinetics, pharmacodynamics, and dose requirements remains poorly understood. Absorption can be affected by the differences in gastric pH and stomach emptying time that have been observed in the pediatric population. Low plasma protein
concentrations and a higher body water composition can change drug distribution. Metabolic processes are often immature at birth, which can lead to a reduced clearance and a prolonged half-life for those drugs for which metabolism is a significant mechanism for elimination. Renal excretion is also reduced in neonates due to immature glomerular filtration, tubular secretion, and reabsorption. Limited data are available on the pharmacodynamic behavior of drugs in the pediatric population.Pediatric Population study Cyp 450.
VLA Comment: Remember children under 3 years old have “immature” cytochrome P450 and 10% of Caucasians for example, are “non-metabolizers”…they cannot metablize many drugs all their lives and become psychotic when given drugs after being diagnosed as ADHD, Autism, etc which are vaccine injuries caused by inability to metabolize the ingredients in vaccines.
Harvard Immunologist to Legislators: Unvaccinated Children Pose ZERO Risk to Anyone
OPEN LETTER TO LEGISLATORS
Dear Legislator:
My name is Tetyana Obukhanych. I hold a PhD in Immunology. I am writing this letter in the hope that it will correct several common misperceptions about vaccines in order to help you formulate a fair and balanced understanding that is supported by accepted vaccine theory and new scientific findings.
Do unvaccinated children pose a higher threat to the public than the vaccinated?
It is often stated that those who choose not to vaccinate their children for reasons of conscience endanger the rest of the public, and this is the rationale behind most of the legislation to end vaccine exemptions currently being considered by federal and state legislators country-wide.
You should be aware that the nature of protection afforded by many modern vaccines – and that includes most of the vaccines recommended by the CDC for children – is not consistent with such a statement. READ MORE… INCLUDES LIST OF VACCINES THAT DO NOT PROTECT THE PUBLIC.