Role of cytokines in the lipopolysaccharide-evoked depression of cytochrome P450 in the brain and liver.
A role for cytokines as mediators of the depression in cytochrome P450 activity in brain and liver during CNS inflammation is proposed.
Genetic polymorphisms, (epigenetic processes) may help uncover underlying mechanisms of action and better identify
susceptible sub-populations. The field is at its infancy, and moving forward there are a number of potentially exciting avenues of research. Below we provide a few examples for both genetics and epigenetics. Study download
The main finding of the report is that glyphosate inhibits cytochrome P450 (CYP) enzymes, a large and diverse group of enzymes that catalyze the oxidation of organic substances. Cytochrome P450 also manages glutathione production and detoxifies street and prescription drugs. …[T]he recent alarming increase in all of these health issues (VLA comment: Autism, ADHD, OCD, Bi Polar, Juveniile Diabetes, Asthma, Obesity, Allergies) etc can be traced back to a combination of gut dysbiosis, impaired sulfate transport, and suppression of the activity of the various members of the cytochrome P450 (CYP) family of enzymes.” Read Dr. Mercola’s report…
VLA comment: Glutathione production is a problem in Autism and Autism spectrum cases. Cytochrome P450 is a necessary metabolic pathway that detoxes the body from toxicity and the modern pain and psyche drugs. 10% of Caucasians are missing their activity of this enzyme and due to their use of street drugs and prescription drugs they are becoming psychotic. Read What is making our kids ans soldiers psychotic?
Cytochrome P450 pathways are also “maturing”. Even if you are a normal metabolizer this metabolic pathway is not mature until around the age of 26. VLA alleges that the immature or non existent activity of this most major detox pathway is unable to handle the toxic assault of 4 vaccine doses in-utero (one with mercury) and 48 vaccine doses by the time the child is six years old, causing the epidemic of Autism, ADHD, OCD, Bi Polar, Juveniile Diabetes, Asthma, Obesity, etc. It is alleged that the white male shooters may be missing this activity. Note they appear to be under the age of 26-James Holmes, Adam Lanza, Columbine shooters, Jerod Loughner. But heretofore the medical cabal refuses to test for the activity of this enysymatic pathway. The test is a mere $275.00.
Laymen’s explanation…NCOW coverletter with extensive links…
Sure looks like Vaccine Injury to me….Heartbreaking documentary. Beware of blaming the genes…that is the effect of some assault, not the cause!
De Novo genetic mutation (spontaneous mutations) are on the rise. (non inherited)
Example: Angelman’s Syndrome…genetic mutation. Symptoms like Autism with a twist. Possible cause…assault on the egg within ART in vitro protoco. In utero flu shots with mercury given to pregnant women since the 1990s.
Studies: Can vaccines and/or psyche drugs given to the population be causing the genetic mutations?
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The report’s findings suggest that pharmaceutical companies have largely ignored recent federal requirements designed to manage the safety of high-risk medications. Americans are at greater risk of injury from dozens of drugs with serious side effects, ranging from birth defects, suicides, homicides to blindness.
For example 10% of Caucasians are non metabolizers of 50% of psyche drugs, pain killers and other pharmacueticals. They are missing, through genetic variation, Cytochrome P450 2D6 the major channel for detoxing drugs. If they are prescribed drugs like Risperdal, Adderal, Haldol, Adivan, etc and they do not have an active Cytochrome P450 2D6 they become more and more psychotic and are apt to commit suicide and/or homicide. Read more about Cytochrome P450
Why are a majority of young mass murderers and school shooters white male (caucasians)? This inexpensive DNA test is not standard of care. Nor are the physicians who prescribe these drugs required to be educated on the subject of drug interactions – pharmacogenetics. FDA REMS DRUG List
Suicide malpractice suits are notoriously difficult to win. Juries, like most people, want to hold individuals responsible for their self-destructive behavior. They are reluctant to blame a suicide on a drug or on a doctor’s negligent behavior. This courtroom victory is consistent with a change that I have been witnessing in my media and public appearances, and in my communications with professionals and laypersons around the world. People are becoming increasingly aware that psychiatric drugs are capable of doing more harm than good, including potentially increasing the risk of violence and suicide. READ ARTICLE…
Read about Pharmageddons dirty secret: What is making our kids psychotic!
There maybe those who object to Dr. Laibow having entitled her video “I AM Adam Lanza’s Mother”. However, I am not one of those dissenting voices. She has taken a cosmic oversoul position. Perhaps she might have capitalized “I AM”. Dr. Laibow serves all of humanity as a potent voice and savior, throwing her powerful spear right between the eyes. She speaks for me, for the safety and health of the humanity. She is right on…she could have said “I AM Eileen Danemann’s voice”, “I AM the Mother of the Universe speaking! Listen to what she is saying. And if you can’t save the world…at least save your own child!
Read What do all these men have in common…
Charles L. Whitfield: Private Practice of Trauma Psychology, Psychiatry, and Addiction Medicine; Consultant and Research
Collaborator at the Centers for Disease Control and Prevention, 3462 Hallcrest Dr., Atlanta, GA 30319-1910, USA and Board of Directors of the Leadership Council on Child Abuse & Interpersonal Violence, Baltimore, MD, USA
Tel.: +404 843 3585; E-mail: c-bwhit@mindspring.com
International Journal of Risk & Safety in Medicine 22 (2010) 195–207 Read study…
Excerpt from Conclusion: These effects of psychiatric drugs are so common and detrimental to the patient that they can no
longer safely or accurately be called “side effects”. Instead, they are more appropriately called toxic
effects.
Excerpt from abstract: These drug effects can be and are often so detrimental to the quality of life among a distinct but significant minority of patients
that they can no longer be considered trivial or unimportant. Instead, they are so disruptive to many patients’ quality of life that
their effect becomes traumatic, and are thereby agents of trauma. These observations and preliminary data may encourage others
to look into this matter in more depth.
Why are some people prone to suicide and homicide and increasing psychosis and some not? Read Dr. Yolande Lucire’s study in pharmacogenetics in which she studies 140 homicidal personalities…a riveting work...must read…
THE HIDDEN GORILLA: Most drugs that can cause suicide, including the antidepressants, mood-stabilizers, antipsychotics, smoking cessation drugs and others, can also cause violence. The akathisia, psychotic decompensation, or emotional disinhibition these drugs trigger that lead some to suicide, lead others to violence (see Healy et al 2006). Read The Hidden Gorilla…
WHAT WOULD BATMAN DO? Why the bifurcation in 1955? This was the year of the introduction of chlorpromazine. Year on year after 1955 a greater number of tranquilizers (antipsychotics / neuroleptics) like chlorpromazine were consumed by veterans with mental health problems as an ever greater number of these drugs were marketed. These drugs were given to veterans who were depressed, anxious or psychotic – they were not as might be thought now restricted to veterans who were schizophrenic. Read article…