Category Archives: RESEARCH, STUDIES, DOCUMENTATION

NEW: 12 Scientific Abstracts 2018

5th International Symposium on Vaccines Features New Findings on Autoimmune Reactions

CMSRI: Symposium Autoimmunity Congress on May 16, 2018, Lisbon, Spain   Read abstracts…

Visualising aluminium in the human brain

Matthew Mold & Christopher Exley, The Birchall Centre, Lennard Jones Laboratories, Keele University, UK.

The evidence for the ASIA syndrome -The registry and epidemiological studies

A. Watad Sheba Medical Center, Department of Medicine ‘B’- Sheba Medical Center- Tel-Hashomer- Israel., Tel Hashomer, Israel

Suspected adverse effects after human papillomavirus vaccination: a temporal relationship between vaccine administration and the appearance of symptoms in Japan

S. Ikeda – Intractable Disease Care Center, Shinshu University Hospital, Matsumoto, Japan

HPV vaccination syndrome. A new tragic fibromyalgia model?

M. Martinez-Lavin1
1Jefe. Departamento de Reumatología, Chief, Rheumatology Department, Instituto Nacional de Cardiología. México

HPV and Lupus: the virus, the vaccine and the disease

Y. Segal1, M. Calabrò2, D. Kanduc3, Y. Shoenfeld1,4
1Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer, affiliated with the Sackler Faculty of Medicine, Tel-Aviv University, Israel
2Department of Emergency and Organ Transplantation, University of Bari, Italy
3Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari,
Italy
4Incumbent of the Laura Schwarz-Kipp chair for research of autoimmune diseases, Sackler
Faculty of Medicine, Tel Aviv University, Israel

Cardiac arrest following HPV vaccination

S. Dahan1,2, Y. Segal1,2, M. Eldar4, D. Kanduc5, Y. Shoenfeld1,3
1Zabludowicz Center for Autoimmune Diseases Sheba Medical Center, Tel-Hashomer, Israel
2Sackler Faculty of Medicine, Tel Aviv University, Israel
3Incumbent of the Laura Schwarz-Kipp chair for research of autoimmune diseases, Sackler
Faculty of Medicine, Tel Aviv University, Israel
4The Neufeld Cardiac Research Institute, The Heart Institute, Chaim Sheba Medical Center,
Ramat Gan, Israel
5Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, Bari,
Italy

Immunogenicity and Safety of Viral and Bacterial Vaccinations in Lupus Subjects

N. Bragazzi1
1University of Genoa, School of Public Health- Department of Health Sciences DISSAL, Genoa, Italy

Elucidating the relationship between the concentration of aluminium salts used in vaccines and the subsequent events occurring at the injection site.

Emma Shardlow, Matthew Mold, Christopher Exley, The Birchall Centre, Lennard-Jones Laboratories, Keele University, UK

Experimental evaluation of the toxicokinetics of aluminum-based adjuvants: what’s wrong in the reference studies?

Jean-Daniel Masson1*, Guillemette Crépeaux1,2*, François-Jérôme Authier1, Christopher Exley3, Romain K Gherardi11 INSERM U955 E10, « Biologie du système neuromusculaire », Faculté de Médecine, Université Paris , France2 Génétique médicale comparée des affections neuromusculaires, Ecole Nationale Vétérinaire d’Alfort, Maisons-Alfort, France3 The Birchall Centre, Lennard-Jones Laboratories, Keele University,  UK

Neurodevelopmental Toxicity of Vaccines in a Rodent Model

Housam Eidi1, Janice Yoo1, Michael Kuo1 and Christopher A. Shaw1 Dept. of Ophthalmology and Visual Sciences, University of British Columbia,  Canada

Cerebral 18F-FDG PET for diagnosing aluminum hydroxide-induced macrophagic myofasciitis

Blanc-Durand Paul, Van Der Gucht Axel, Guedj Eric, Aoun-Sebaiti Mehdi, Gherardi Romain K., Itti Emmanuel, Authier F. Jérôme Reference Center for Neuromuscular Disorders, H. Mondor Hospital, Assistance Publique-Hôpitaux de Paris ; INSERM U955-Team 10, Paris Est-Creteil University, France. (10) INSERM U955-GRC Amyloid Research Institute, Créteil, France.

Clinicopathologic studies in lambs repetitively inoculated with aluminum adjuvant containing products

Asín1, J. Molín1, M. Pérez1, P. Pinczowski1, M. Gimeno1, M Pascual-Alonso1, N. Navascués, A1. Muniesa1, I. de Blas1, G. María1, D. Lacasta1, A. Fernández1, L. de Pablo2, M. Mold3, C. Exley3, D. de Andrés2, R. Reina2, L. Luján1 1. University of Zaragoza, Spain 2. Institute of Agrobiotechnology, CSIC-Public University of Navarra, Spain 3. The Birchall Centre, Keele University, Keele, Staffordshire, UK

STUDY: ADJUVANTS and their effects-ASIA

The value of Autoimmune Syndrome Induced by Adjuvant
(ASIA)

Autoimmune Syndrome Induced by Adjuvant (ASIA) is a definition aimed to describe the common etiological process at the root of five clinical entities sharing similar symptomatology: macrophagic myofasciitis syndrome (MMF), GulfWar Syndrome (GWS), sick building syndrome (SBS), siliconosis, and post-vaccination autoimmune phenomena.

ASIAReview

VLA COMMENT:  FLUAD is a new experimental vaccine for senior.  It contains the same adjuvant at that which is used in the Anthrax vaccine causing “Gulf War syndrome”.  Watch Direct order

Professional Comments: Last Year’s Failed Flu Vaccine

The Painful Truth About Last Year’s Failed Flu Vaccine

“…most ‘flu’ appears to have nothing to do with influenza. Every year, hundreds of thousands of respiratory specimens are tested across the US. Of those tested, on average 16% are found to be influenza positive.” – From the British Medical Journal editor, Peter Doshi, MD

“71 people would need to be treated with the flu vaccine to prevent one case. In other words, the flu vaccine did nothing for 70 out of 71 who received it. That means this study found the flu vaccine failed 99% (70/71).” — Dr David Brownstein

“Under ideal conditions (when the vaccine actually matches the main viruses circulating that season) you need to vaccinate 33 healthy adults to avoid one set of influenza symptoms. 33 is what is called the NNV (Number Needed to Vaccinate).” – Dr Tom Jefferson of the Cochrane Collaboration (Cochrane Database Syst. Rev. 2018. Feb. 1,2:CD001269)

“…influenza virus often mutates to adapt to being grown in chicken eggs, which can influence antigenicity and hence vaccine effectiveness.” — Ian A. Wilson, MD, et al from: “A Structural Explanation for the Low Effectiveness of the Seasonal Influenza H3N2 Vaccine. (http://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1006682)

“Between 33 and 100 people are needed to vaccinate to prevent one case of flu symptoms.” – Alan Cassals, author of Selling Sickness: Medical Screening and the Misguided Hunt for Disease

“Normally, the flu vaccine is between 50 to 60 percent effective.” — Dr. Tom Frieden, Director of the Centers for Disease Control and Prevention (CDC)

VLA COMMENT: BYW…The shingles vaccines is 90% ineffective for seniors.

Aluminum in Vaccines: Mice behave with symptoms of Autism

First Experimental Study on Baby Mice Finds Autism-like Response to Common Vaccine Ingredient

A breakthrough study by scientists from the University of British Columbia in Vancouver, Canada has been published in the Journal of Inorganic Biochemistry demonstrating that significant correlations exist between rates of Autism Spectrum Disorder (ASD) and total aluminum adjuvants given to children through vaccines in several Western countries.

This is the first experimental study to demonstrate that aluminum adjuvants can impair social behavior if applied in the early period of postnatal development.

An infant in the United States, in its first two years, usually receives 27 vaccines as part of the routine pediatric vaccination schedule; many of which contain aluminum adjuvants.

Read More…

Best Aluminum Studies

DOWNLOAD HOTLINKS TO THE STUDIES BELOW

Best Aluminium Studies DOWNLOAD HOTLINKS TO THE STUDIES BELOW

Ahmed SS, Steinman L. 2017. Narcolepsy and influenza vaccination-induced autoimmunity.Ann Transl Med. 5(1):25. doi: 10.21037/atm.2016.12.63.

Crépeaux G, Eidi H, David MO, Baba-Amer Y, Tzavara E, Giros B, Authier FJ, Exley C, Shaw CA, Cadusseau J, Gherardi RK. 2017. Non-linear dose-response of aluminium hydroxide adjuvant particles: Selective low dose neurotoxicity. Toxicology. 375:48-57. doi: 10.1016/j.tox.2016.11.018.

Lyons-Weiler, J and R. Ricketson. 2018. Reconsideration of the Immunotherapeutic Pediatric Safe Dose Levels of Aluminum. Journal and Trace Elements in Medicine and Biology 48:67-73.

Lyons-Weiler, J. 2018b. Autism is an Acquired Cellular Detoxification Deficiency Syndrome with Heterogeneous Genetic Predisposition. Autism Open Access 8(1):1-17. doi: 10.4172/2165-7890.1000224

Masson JD, Crépeaux G, Authier FJ, Exley C, Gherardi RK. 2018. Critical analysis of reference studies on the toxicokinetics of aluminum-based adjuvants. J Inorg Biochem. 181:87-95. doi: 10.1016/j.jinorgbio.2017.12.015.

Mold M, Umar D, King A, Exley C. 2018. Aluminium in brain tissue in autism. J Trace Elem Med Biol. 46:76-82. doi: 10.1016/j.jtemb.2017.11.012.

Morris G, Puri BK, Frye RE. 2017. The putative role of environmental aluminium in the development of chronic neuropathology in adults and children. How strong is the evidence and what could be the mechanisms involved? Metab Brain Dis.;32(5):1335-1355. doi: 10.1007/s11011-017-0077-2.

Sokol DK, Chen D, Farlow MR, Dunn DW, Maloney B, Zimmer JA, Lahiri DK. 2006. High levels of Alzheimer beta-amyloid precursor protein (APP) in children with severely autistic behavior and aggression.  J Child Neurol. 21(6):444-9.

Stamogiannos A, Papakyriakou A, Mauvais FX, van Endert P, Stratikos E 2016. Screening Identifies Thimerosal as a Selective Inhibitor of Endoplasmic Reticulum Aminopeptidase 1.  ACS Med Chem Lett. 7(7):681-5. doi: 10.1021/acsmedchemlett.6b00084.

Aluminum too high in Pediatric vaccines

JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

On Day 1 of life, infants receive 17 times more aluminum than would be allowed if doses were adjusted per body weight.

Abstract

FDA regulations require safety testing of constituent ingredients in drugs (21 CFR 610.15). With the exception of extraneous proteins, no component safety testing is required for vaccines or vaccine schedules. The dosing of aluminum in vaccines is based on the production of antibody titers, not safety science. Here we estimate a Pediatric Dose Limit that considers body weight. We identify several serious historical missteps in past analyses of provisional safe levels of aluminum in vaccines, and provide updates relevant to infant aluminum exposure in the pediatric schedule considering pediatric body weight

READ….

CDC’s view of Aluminum

The small quantity of aluminum retained in the body
accumulates over time. Most of the aluminum that accumulates
(50 to 60 percent) settles in the bones, some in the lungs (about 25
percent) and some in the brain (about 1 percent). The remaining
quantities are distributed in serum, skin, gastrointestinal tract, lymph
nodes and glands. In fact, low quantities of aluminum can be found
in most organs.

VLA comment:  Apparently it is okay with the CDC and Paul Offit at the Philadelphia Children’s Hospital that…and I quote and excerpt…the process which a small infant has to deal with excreting this poison or the consequences of retain the metal in the bones or the brains is inconsequental:

 

 

Pharmacokinetics…aluminum adjuvant Pertussis Vaccine and Allergies

Pharmacokinetics and Differential Regulation of Cytochrome P450 Enzymes in Type 1 Allergic Mice

“We investigated hepatic P450 metabolism and drug pharmacokinetics in type 1 allergic mice induced by ovalbumin (OVA) emulsified with aluminum and inactive Bordetella pertussis. To further propose a possible key factor in drug-allergic disease interactions, we examined the inhibitory effect of NO, a marker of allergic conditions on the activities of major P450 isoforms”.

Read study…

Journal of Immunotoxology (2011) VACCINES & AUTISM

The article in the Journal of Immunotoxicology is entitled Theoretical Aspects of Autism: Causes-A Review Theoretical aspects of autism Causes A review The author is Helen Ratajczak, surprisingly herself a former senior scientist at a pharmaceutical firm. Ratajczak did what nobody else apparently has bothered to do: she reviewed the body of published science since autism was first described in 1943. Not just one theory suggested by research such as the role of MMR shots, or the mercury preservative thimerosal; but all of them.

HUMAN DNA IN VACCINES (EXCERPT)

That DNA is incorporated into the host DNA. Now it’s changed, altered self and body kills it. Where is this most expressed? The neurons of the brain. Now you have body killing the brain cells and it’s an ongoing inflammation. It doesn’t stop, it continues through the life of that individual.”

READ MORE….

Pigs: Genetic alteration

Not only have pigs been fed Ractopamine for years in the USA, which makes them leaner but may give humans a heart attack.  What’s more the drug is banned in 160 countries including China.  Since China took over Smithfield, the leader in USA hog production, one would only hope that they have eliminated the practice.  However, here is something novel in the Food industry.

2 US companies have teamed up to jointly cooperate on a breeding plan to have male piglets born castrated.  Read More…

VLA Comment:  Most religious and metaphysical organizations and their practioners do not eat pork.  Good thinking!

Magic Mushrooms and some individual’s inability to metabolize-causing psychosis

Magic Mushrooms and some individual’s inability to metabolize-causing psychosis, albeit temporary

Magic Mushrooms:  Some individuals are not able to metabolize-causing psychosis, albeit temporary and not to be confused with “mental illness”.

Indolealkylamines: Biotransformations and Potential Drug–Drug Interactions (STUDY)

Increased knowledge in this area may advance our understanding of individual vulnerability to and/or protection from illicit drugs of abuse (). This review, therefore, aims to describe our current understanding of the metabolism  READ STUDY…